| Literature DB >> 24534106 |
Benjamin J Ayers1, Jacqueline Hollinshead2, Alexander W Saville3, Shinpei Nakagawa4, Isao Adachi4, Atsushi Kato4, Ken Izumori5, Barbara Bartholomew2, George W J Fleet3, Robert J Nash6.
Abstract
Iteamine, o-aminobenzyl β-D-glucopyranoside, is the first alkaloid to be isolated from Itea virginica. Itea is the sole plant source of D-psicose, a rare sugar likely to be a major dietary supplement. The structure of iteamine was established by NMR and confirmed by total synthesis. Iteamine and its galacto-analog (which was not found in Itea plants) showed no strong inhibition of any of the 15 glycosidases tested; unnatural galacto-iteamine was a weak inhibitor of chicken liver α-N-acetylgalactosaminidase.Entities:
Keywords: Grossulariaceae; Itea virginica; Iteamine; d-Psicose; α-N-acetylgalactosaminidase
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Year: 2014 PMID： 24534106 DOI： 10.1016/j.phytochem.2014.01.012
Source DB: PubMed Journal: Phytochemistry ISSN： 0031-9422 Impact factor: 4.072