Literature DB >> 24533373

A rational approach to the management of obstructive sleep apnea syndrome.

P Vijaya Krishnan1, S Raghunandhan1, R S Anand Kumar1, Mohan Kameswaran1.   

Abstract

Snoring & obstructive sleep apnea syndrome (OSAS) is a globally prevalent problem which is on the rise in recent times. The treatment modalities include medical appliances and surgery. It is mandatory to have a rational approach in the management of OSAS, by meticulously analyzing both anatomical and physiological parameters causing the disorder. To define a rational approach for the management of OSAS, by devising a comprehensive protocol with assessment of anatomical level of obstruction by dynamic MRI and physiological factors by Epworth sleepiness scale (ESS) and Polysomnography. A prospective study in 110 patients was conducted over a period of 2 years, at our institute. All patients in the study group were evaluated with dynamic MRI and ESS and Polysomnography. As per the management protocols defined in the study, surgery was advocated in 46 patients (Group 1) with severe compromise in airway, while another group of 64 patients (Group 2) were provided continuous positive airway pressure support (CPAP). Successful outcomes among these 110 patients were analyzed at the end of the study period. A few patients required multimodal therapy which included surgery and CPAP support. Among 46 patients, surgical treatment proved successful in 41 patients in whom AHI reduced from 46.96 to 12.88 (improved by 62%) and ESS improved by almost ten points. Among 64 patients in CPAP group, AHI reduced from 54.2 to 11.3 (improved by 79%) and ESS improved by 11 points in all the patients, but six of them had poor compliance. Five patients among the surgical group had persistence of symptoms. Inferences derived from the above results proved the success of formulating a rational approach in the management of OSAS. Critical analysis of the anatomical and physiological factors inducing obstructive episodes and an appropriate treatment plan is vital, to produce successful outcomes in patients with OSAS. Failure of surgical procedures, are often due to improper case selection. A small group of patients may require multimodal therapy with surgery and CPAP.

Entities:  

Keywords:  Epworth sleepiness scale; Obstructive sleep apnea syndrome; Polysomnography; Respiratory distress index; Sleep MRI

Year:  2012        PMID: 24533373      PMCID: PMC3918327          DOI: 10.1007/s12070-011-0381-9

Source DB:  PubMed          Journal:  Indian J Otolaryngol Head Neck Surg        ISSN: 2231-3796


  20 in total

1.  Early polysomnographic findings and long-term subjective results in sleep apnea patients treated with laser-assisted uvulopalatoplasty.

Authors:  R P Walker; T Garrity; C Gopalsami
Journal:  Laryngoscope       Date:  1999-09       Impact factor: 3.325

2.  Continuous positive airway pressure therapy for treating sleepiness in a diverse population with obstructive sleep apnea: results of a meta-analysis.

Authors:  Sanjay R Patel; David P White; Atul Malhotra; Michael L Stanchina; Najib T Ayas
Journal:  Arch Intern Med       Date:  2003-03-10

3.  Obstructive sleep apnea syndrome: a review of 306 consecutively treated surgical patients.

Authors:  R W Riley; N B Powell; C Guilleminault
Journal:  Otolaryngol Head Neck Surg       Date:  1993-02       Impact factor: 3.497

4.  Prevalence of persistent sleep apnea in patients treated with continuous positive airway pressure.

Authors:  Marcel A Baltzan; Ibrahim Kassissia; Osama Elkholi; Mark Palayew; Richard Dabrusin; Norman Wolkove
Journal:  Sleep       Date:  2006-04       Impact factor: 5.849

5.  Uvulopalatopharyngoplasty and inferior sagittal mandibular osteotomy with genioglossus advancement for treatment of obstructive sleep apnea.

Authors:  N T Johnson; J Chinn
Journal:  Chest       Date:  1994-01       Impact factor: 9.410

6.  Temporary tracheotomy in the surgical treatment of obstructive sleep apnea syndrome: personal experience.

Authors:  A Campanini; A De Vito; S Frassineti; C Vicini
Journal:  Acta Otorhinolaryngol Ital       Date:  2003-12       Impact factor: 2.124

Review 7.  The efficacy of surgical modifications of the upper airway in adults with obstructive sleep apnea syndrome.

Authors:  A E Sher; K B Schechtman; J F Piccirillo
Journal:  Sleep       Date:  1996-02       Impact factor: 5.849

8.  Polysomnographic effects of nasal surgery for snoring and obstructive sleep apnea.

Authors:  Sun Tae Kim; Jin Ho Choi; Heung Gyu Jeon; Heung Eog Cha; Dong Young Kim; Yoo-Sam Chung
Journal:  Acta Otolaryngol       Date:  2004-04       Impact factor: 1.494

9.  The long-term evaluation of tracheostomy in the management of severe obstructive sleep apnea.

Authors:  Gentry W Thatcher; Robert H Maisel
Journal:  Laryngoscope       Date:  2003-02       Impact factor: 3.325

10.  Inferior sagittal osteotomy with hyoid bone suspension for obese patients with sleep apnea.

Authors:  S G Ramirez; D I Loube
Journal:  Arch Otolaryngol Head Neck Surg       Date:  1996-09
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