Mary C Davis1, Kirti Thummala, Alex J Zautra. 1. Department of Psychology, Arizona State University, P.O. Box 1104, Tempe, AZ, 85287-1104, USA, mary.davis@asu.edu.
Abstract
BACKGROUND: Chronic pain with comorbid depression is characterized by poor mood regulation and stress-related pain. PURPOSE: This study aims to compare depressed and non-depressed pain patients in mood and pain stress reactivity and recovery, and test whether a post-stress positive mood induction moderates pain recovery. METHODS:Women with fibromyalgia and/or osteoarthritis (N = 110) underwent interpersonal stress and were then randomly assigned by pain condition and depression status, assessed via the Center for Epidemiological Studies-Depression scale, to positive versus neutral mood induction. RESULTS: Depression did not predict stress-related reactivity in despondency, joviality, or clinical pain. However, depression × mood condition predicted recovery in joviality and clinical pain; depressed women recovered only in the positive mood condition, whereas non-depressed women recovered in both mood conditions. CONCLUSIONS: Depression does not alter pain and mood stress reactivity, but does impair recovery. Boosting post-stress jovial mood ameliorates pain recovery deficits in depressed patients, a finding relevant to chronic pain interventions.
RCT Entities:
BACKGROUND:Chronic pain with comorbid depression is characterized by poor mood regulation and stress-related pain. PURPOSE: This study aims to compare depressed and non-depressed painpatients in mood and pain stress reactivity and recovery, and test whether a post-stress positive mood induction moderates pain recovery. METHODS:Women with fibromyalgia and/or osteoarthritis (N = 110) underwent interpersonal stress and were then randomly assigned by pain condition and depression status, assessed via the Center for Epidemiological Studies-Depression scale, to positive versus neutral mood induction. RESULTS:Depression did not predict stress-related reactivity in despondency, joviality, or clinical pain. However, depression × mood condition predicted recovery in joviality and clinical pain; depressedwomen recovered only in the positive mood condition, whereas non-depressedwomen recovered in both mood conditions. CONCLUSIONS:Depression does not alter pain and mood stress reactivity, but does impair recovery. Boosting post-stress jovial mood ameliorates pain recovery deficits in depressedpatients, a finding relevant to chronic pain interventions.
Authors: Thorsten Giesecke; David A Williams; Richard E Harris; Thomas R Cupps; Xiaoming Tian; Thomas X Tian; Richard H Gracely; Daniel J Clauw Journal: Arthritis Rheum Date: 2003-10