Literature DB >> 24531885

Wnt/β-catenin signaling inhibits the Shh pathway and impairs tumor growth in Shh-dependent medulloblastoma.

Julia Pöschl1, Martin Bartels, Jasmin Ohli, Edoardo Bianchi, Konstantin Kuteykin-Teplyakov, Daniel Grammel, Julia Ahlfeld, Ulrich Schüller.   

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Year:  2014        PMID： 24531885     DOI： 10.1007/s00401-014-1258-2

Source DB:  PubMed          Journal:  Acta Neuropathol        ISSN： 0001-6322            Impact factor:   17.088


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  11 in total

1.  Inhibition of WNT signaling attenuates self-renewal of SHH-subgroup medulloblastoma.

Authors:  J Rodriguez-Blanco; L Pednekar; C Penas; B Li; V Martin; J Long; E Lee; W A Weiss; C Rodriguez; N Mehrdad; D M Nguyen; N G Ayad; P Rai; A J Capobianco; D J Robbins
Journal:  Oncogene       Date:  2017-07-17       Impact factor: 9.867

Review 2.  Sonic Hedgehog Signaling in Cerebellar Development and Cancer.

Authors:  Wanchen Wang; Ryo Shiraishi; Daisuke Kawauchi
Journal:  Front Cell Dev Biol       Date:  2022-04-29

3.  Antagonism between Hedgehog and Wnt signaling pathways regulates tumorigenicity.

Authors:  Mei Ding; Xin Wang
Journal:  Oncol Lett       Date:  2017-09-22       Impact factor: 2.967

4.  GSK-3 modulates SHH-driven proliferation in postnatal cerebellar neurogenesis and medulloblastoma.

Authors:  Jennifer K Ocasio; Rolf Dale P Bates; Carolyn D Rapp; Timothy R Gershon
Journal:  Development       Date:  2019-10-10       Impact factor: 6.868

5.  A mouse model for embryonal tumors with multilayered rosettes uncovers the therapeutic potential of Sonic-hedgehog inhibitors.

Authors:  Julia E Neumann; Annika K Wefers; Sander Lambo; Edoardo Bianchi; Marie Bockstaller; Mario M Dorostkar; Valerie Meister; Pia Schindler; Andrey Korshunov; Katja von Hoff; Johannes Nowak; Monika Warmuth-Metz; Marlon R Schneider; Ingrid Renner-Müller; Daniel J Merk; Mehdi Shakarami; Tanvi Sharma; Lukas Chavez; Rainer Glass; Jennifer A Chan; M Mark Taketo; Philipp Neumann; Marcel Kool; Ulrich Schüller
Journal:  Nat Med       Date:  2017-09-11       Impact factor: 53.440

Review 6.  Medulloblastoma drugs in development: Current leads, trials and drawbacks.

Authors:  Jiachen Wen; M Kyle Hadden
Journal:  Eur J Med Chem       Date:  2021-02-08       Impact factor: 6.514

7.  Crosstalk of the Wnt/β-catenin pathway with other pathways in cancer cells.

Authors:  Saint-Aaron L Morris; Suyun Huang
Journal:  Genes Dis       Date:  2016-01-06

8.  Neoplastic and immune single-cell transcriptomics define subgroup-specific intra-tumoral heterogeneity of childhood medulloblastoma.

Authors:  Kent A Riemondy; Sujatha Venkataraman; Nicholas Willard; Anandani Nellan; Bridget Sanford; Andrea M Griesinger; Vladimir Amani; Siddhartha Mitra; Todd C Hankinson; Michael H Handler; Martin Sill; Jennifer Ocasio; Seth J Weir; Daniel S Malawsky; Timothy R Gershon; Alexandra Garancher; Robert J Wechsler-Reya; Jay R Hesselberth; Nicholas K Foreman; Andrew M Donson; Rajeev Vibhakar
Journal:  Neuro Oncol       Date:  2022-02-01       Impact factor: 13.029

9.  β-Catenin-Gli1 interaction regulates proliferation and tumor growth in medulloblastoma.

Authors:  Jenny Zinke; Fabian T Schneider; Patrick N Harter; Sonja Thom; Nicole Ziegler; Rune Toftgård; Karl H Plate; Stefan Liebner
Journal:  Mol Cancer       Date:  2015-02-03       Impact factor: 27.401

Review 10.  Subgroup-Specific Diagnostic, Prognostic, and Predictive Markers Influencing Pediatric Medulloblastoma Treatment.

Authors:  Sutapa Ray; Nagendra K Chaturvedi; Kishor K Bhakat; Angie Rizzino; Sidharth Mahapatra
Journal:  Diagnostics (Basel)       Date:  2021-12-28
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