| Literature DB >> 24530822 |
Pietro E Cippà1, Ariana Gaspert2, Christoph Etter1, Zehra Guenduez3, Sylvie Ferrari-Lacraz4, Barbara Rüsi3, Thomas Fehr5.
Abstract
The role of donor HLA-DP-specific antibodies after renal transplantation is controversial, and only preformed HLA-DP-specific antibodies have been shown to mediate rejection. Here we present a case of late humoral rejection mediated by de novo donor HLA-DP-specific antibodies in a non-sensitized recipient. This unique case demonstrates the pathogenic role of de novo anti-DP antibodies and suggests that HLA-DP matching might be relevant for renal transplantation.Entities:
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Year: 2014 PMID： 24530822 DOI： 10.1016/j.humimm.2014.02.008
Source DB: PubMed Journal: Hum Immunol ISSN： 0198-8859 Impact factor: 2.850