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Literature DB >> 24529711

Recent advances in ophthalmic molecular imaging.

J Emanuel Ramos de Carvalho¹, Frank D Verbraak², Maurice C Aalders³, Cornelis J van Noorden⁴, Reinier O Schlingemann⁵.

Abstract

The aim of molecular imaging techniques is the visualization of molecular processes and functional changes in living animals and human patients before morphological changes occur at the cellular and tissue level. Ophthalmic molecular imaging is still in its infancy and has mainly been used in small animals for pre-clinical research. The goal of most of these pre-clinical studies is their translation into ophthalmic molecular imaging techniques in clinical care. We discuss various molecular imaging techniques and their applications in ophthalmology.

Entities: Species

Keywords: eye; magnetic resonance imaging; molecular imaging; multispectral imaging; ophthalmic imaging; ophthalmology; optical coherence tomography; optical imaging; scanning laser ophthalmoscope

Mesh：

Year: 2013 PMID： 24529711 DOI： 10.1016/j.survophthal.2013.09.005

Source DB: PubMed Journal: Surv Ophthalmol ISSN： 0039-6257 Impact factor: 6.048

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Cited

16 in total

1. Catalase therapy corrects oxidative stress-induced pathophysiology in incipient diabetic retinopathy.

Authors: Courtney R Giordano; Robin Roberts; Kendra A Krentz; David Bissig; Deepa Talreja; Ashok Kumar; Stanley R Terlecky; Bruce A Berkowitz
Journal: Invest Ophthalmol Vis Sci Date: 2015-05 Impact factor: 4.799

2. Systemic Retinaldehyde Treatment Corrects Retinal Oxidative Stress, Rod Dysfunction, and Impaired Visual Performance in Diabetic Mice.

Authors: Bruce A Berkowitz; Timothy S Kern; David Bissig; Priya Patel; Ankit Bhatia; Vladimir J Kefalov; Robin Roberts
Journal: Invest Ophthalmol Vis Sci Date: 2015-10 Impact factor: 4.799

3. In vivo imaging of prodromal hippocampus CA1 subfield oxidative stress in models of Alzheimer disease and Angelman syndrome.

Authors: Bruce A Berkowitz; Jacob Lenning; Nikita Khetarpal; Catherine Tran; Johnny Y Wu; Ali M Berri; Kristin Dernay; E Mark Haacke; Fatema Shafie-Khorassani; Robert H Podolsky; John C Gant; Shaniya Maimaiti; Olivier Thibault; Geoffrey G Murphy; Brian M Bennett; Robin Roberts
Journal: FASEB J Date: 2017-06-07 Impact factor: 5.191

4. Genetic dissection of horizontal cell inhibitory signaling in mice in complete darkness in vivo.

Authors: Bruce A Berkowitz; Geoffrey G Murphy; Cheryl Mae Craft; D James Surmeier; Robin Roberts
Journal: Invest Ophthalmol Vis Sci Date: 2015-05 Impact factor: 4.799

Review 5. Cancer-Associated, Stimuli-Driven, Turn on Theranostics for Multimodality Imaging and Therapy.

Authors: Xingshu Li; Jihoon Kim; Juyoung Yoon; Xiaoyuan Chen
Journal: Adv Mater Date: 2017-03-29 Impact factor: 30.849

6. Development of an MRI biomarker sensitive to tetrameric visual arrestin 1 and its reduction via light-evoked translocation in vivo.

Authors: Bruce A Berkowitz; Jawan Gorgis; Ankit Patel; Faiza Baameur; Vsevolod V Gurevich; Cheryl M Craft; Vladimir J Kefalov; Robin Roberts
Journal: FASEB J Date: 2014-10-28 Impact factor: 5.191

Recent advances in ophthalmic molecular imaging.

1. Catalase therapy corrects oxidative stress-induced pathophysiology in incipient diabetic retinopathy.

2. Systemic Retinaldehyde Treatment Corrects Retinal Oxidative Stress, Rod Dysfunction, and Impaired Visual Performance in Diabetic Mice.

3. In vivo imaging of prodromal hippocampus CA1 subfield oxidative stress in models of Alzheimer disease and Angelman syndrome.

4. Genetic dissection of horizontal cell inhibitory signaling in mice in complete darkness in vivo.

Review 5. Cancer-Associated, Stimuli-Driven, Turn on Theranostics for Multimodality Imaging and Therapy.

6. Development of an MRI biomarker sensitive to tetrameric visual arrestin 1 and its reduction via light-evoked translocation in vivo.

7. Oxidative stress and light-evoked responses of the posterior segment in a mouse model of diabetic retinopathy.

Review 8. Preventing diabetic retinopathy by mitigating subretinal space oxidative stress in vivo.

9. Differential volume regulation and calcium signaling in two ciliary body cell types is subserved by TRPV4 channels.

Review 10. MRI of rod cell compartment-specific function in disease and treatment in vivo.