| Literature DB >> 24529416 |
Vittorio Mantero1, Andrea Rigamonti2, Sergio Valentini3, Anna Fiumani2, Francesca Piamarta2, Paolo Bonfanti4, Andrea Salmaggi2.
Abstract
We present a case of zoster sine herpete causing isolated acute dysphagia in an immunocompetent patient. The interest of this paper is the atypical presentation of varicella-zoster virus reactivation. A 77-year-old woman presented with a 3-day history of fever and worsening dysphagia for both liquid and solid foods. Cerebrospinal fluid examination revealed lymphocytic pleocytosis and PCR amplified varicella-zoster virus DNA with high antibody titers in both serum and cerebrospinal fluid. The panel was suggestive of a cranial neuritis due to varicella-zoster virus, involved cranial nerves, even in the absence of a cutaneous and mucosal rash. Varicella-zoster virus reactivation should be included in the differential diagnosis of isolated or multiple cranial nerve palsies, with or without zosteriform skin lesions. A prompt etiologic diagnosis can lead to early administration of antiviral therapy.Entities:
Keywords: Cerebrospinal fluid examination; Cranial neuritis; Dysphagia; Varicella-zoster virus; Viral infections
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Year: 2014 PMID: 24529416 DOI: 10.1016/j.jcv.2014.01.008
Source DB: PubMed Journal: J Clin Virol ISSN: 1386-6532 Impact factor: 3.168