Literature DB >> 24529369

miniMAVS, You Complete Me!

Manira Rayamajhi1, Edward A Miao1, Nathaniel J Moorman2.   

Abstract

The functional significance of protein diversification through translational regulation in mammals is largely unexplored. Brubaker et al. now describe the generation of two functionally distinct mammalian proteins, MAVS and miniMAVS, from a single bicistronic mRNA and suggest that noncanonical translation may impact multiple players in innate immune regulation.
Copyright © 2014 Elsevier Inc. All rights reserved.

Entities:  

Mesh：

Substances：

Year:  2014        PMID： 24529369      PMCID： PMC5097455          DOI： 10.1016/j.cell.2014.01.045

Source DB:  PubMed          Journal:  Cell        ISSN： 0092-8674            Impact factor:   41.582


  7 in total

1.  p53 Stability and activity is regulated by Mdm2-mediated induction of alternative p53 translation products.

Authors:  Yili Yin; C W Stephen; M Gloria Luciani; Robin Fåhraeus
Journal:  Nat Cell Biol       Date:  2002-06       Impact factor: 28.824

2.  Signaling organelles of the innate immune system.

Authors:  Jonathan C Kagan
Journal:  Cell       Date:  2012-12-07       Impact factor: 41.582

3.  Alternative translation of osteopontin generates intracellular and secreted isoforms that mediate distinct biological activities in dendritic cells.

Authors:  Mari L Shinohara; Hye-Jung Kim; June-Ho Kim; Virgilio A Garcia; Harvey Cantor
Journal:  Proc Natl Acad Sci U S A       Date:  2008-05-14       Impact factor: 11.205

4.  An imprinted, mammalian bicistronic transcript encodes two independent proteins.

Authors:  T A Gray; S Saitoh; R D Nicholls
Journal:  Proc Natl Acad Sci U S A       Date:  1999-05-11       Impact factor: 11.205

5.  Ribosome profiling of mouse embryonic stem cells reveals the complexity and dynamics of mammalian proteomes.

Authors:  Nicholas T Ingolia; Liana F Lareau; Jonathan S Weissman
Journal:  Cell       Date:  2011-11-03       Impact factor: 41.582

6.  Identification of alternatively translated Tetherin isoforms with differing antiviral and signaling activities.

Authors:  Luis J Cocka; Paul Bates
Journal:  PLoS Pathog       Date:  2012-09-27       Impact factor: 6.823

Review 7.  Pushing the limits of the scanning mechanism for initiation of translation.

Authors:  Marilyn Kozak
Journal:  Gene       Date:  2002-10-16       Impact factor: 3.688
  7 in total
  1 in total

1.  Viperin interaction with mitochondrial antiviral signaling protein (MAVS) limits viperin-mediated inhibition of the interferon response in macrophages.

Authors:  Jia Shee Hee; Peter Cresswell
Journal:  PLoS One       Date:  2017-02-16       Impact factor: 3.240
  1 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.