Literature DB >> 2452752

The prostaglandin response in guinea-pig taenia caeci and trachea smooth muscle of different ages.

N A Vermue1, A Den Hertog.   

Abstract

The concentration-response curves for the carbachol-induced contraction of smooth muscle cells of guinea-pig taenia caeci and trachea were not dependent on tissue age. The prostaglandin E2 and F2 alpha responses increased with age in taenia caeci in contrast with the PGE2 response evoked in trachea. The high-potassium responses evoked in taenia caeci and trachea both increased at higher tissue age. Methoxyverapamil only inhibited the age-dependent responses. The results suggest that it is mainly the voltage-dependent calcium channels that are involved in the age-dependent prostaglandin response.

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Year:  1988        PMID: 2452752     DOI: 10.1016/0014-2999(88)90786-8

Source DB:  PubMed          Journal:  Eur J Pharmacol        ISSN: 0014-2999            Impact factor:   4.432


  2 in total

1.  Differential responsiveness to contractile agents of isolated smooth muscle cells from human colons as a function of age and inflammation.

Authors:  J C Boyer; C Guitton; C Pignodel; P Cuq; P Moussu; P Pouderoux; M O Christen; J L Balmes; J P Bali
Journal:  Dig Dis Sci       Date:  1997-11       Impact factor: 3.199

2.  Action of propranolol in the reaction of smooth musculature of tracheal rings induced with acetylcholine, histamine, serotonin (5-HT) and prostaglandin (PGF2-alfa) in vitro and in vivo.

Authors:  Hilmi Islami; Sadi Bexheti; Halil Ahmetaj; Aziz Sukalo; Suzana Manxhuka; Bajram Nuraj; Xhevat Kamberi; Shaip Krasniqi; Hasime Qorraj; Bashkim Kastrati; Mentor Disha
Journal:  Bosn J Basic Med Sci       Date:  2009-05       Impact factor: 3.363

  2 in total

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