Literature DB >> 24527383

Evaluation of the potentials of autologous blood injection for healing in diabetic foot ulcers.

Mohammed Al Azrak1, Taher Ismail2, Olfat Shaker3.   

Abstract

Healing is a complex multifactorial process, hence it is not easy to be studied accurately. In this paper we tried to demonstrate the potentials of application of autologous blood by injection into the raw areas and ulcers of three diabetic patients using their blood as an alternative to synthesized and cultured stem cells or growth factors. It was found that a natural easily obtained blood can be used to enrich the media of the wound. Also it was applicable in relation to its cost-effectiveness as well as availability. The healing process was accelerated in the injected side more than the non-injected one.

Entities:  

Keywords:  Autologous blood; Blood injection; Diabetic ulcers; Healing

Year:  2013        PMID: 24527383      PMCID: PMC3921244          DOI: 10.1016/j.jccw.2013.06.006

Source DB:  PubMed          Journal:  J Am Coll Clin Wound Spec        ISSN: 2213-5103


  28 in total

Review 1.  Cutaneous wound healing.

Authors:  A J Singer; R A Clark
Journal:  N Engl J Med       Date:  1999-09-02       Impact factor: 91.245

2.  Modeling dermal granulation tissue with the linear fibroblast-populated collagen matrix: a comparison with the round matrix model.

Authors:  Mark J Eichler; Mark A Carlson
Journal:  J Dermatol Sci       Date:  2005-10-12       Impact factor: 4.563

3.  The role of the macrophage in wound repair. A study with hydrocortisone and antimacrophage serum.

Authors:  S J Leibovich; R Ross
Journal:  Am J Pathol       Date:  1975-01       Impact factor: 4.307

Review 4.  Leukemia inhibitory factor, Interleukin 6, and other cytokines using the GP130 transducing receptor: roles in inflammation and injury.

Authors:  R A Gadient; P H Patterson
Journal:  Stem Cells       Date:  1999       Impact factor: 6.277

5.  Effect of extensive debridement and treatment on the healing of diabetic foot ulcers. Diabetic Ulcer Study Group.

Authors:  D L Steed; D Donohoe; M W Webster; L Lindsley
Journal:  J Am Coll Surg       Date:  1996-07       Impact factor: 6.113

Review 6.  Stem cell use in critical limb ischemia.

Authors:  R Kolvenbach; C Kreissig; E Ludwig; C Cagiannos
Journal:  J Cardiovasc Surg (Torino)       Date:  2007-02       Impact factor: 1.888

7.  Matrix contraction by dermal fibroblasts requires transforming growth factor-beta/activin-linked kinase 5, heparan sulfate-containing proteoglycans, and MEK/ERK: insights into pathological scarring in chronic fibrotic disease.

Authors:  Yunliang Chen; Xu Shi-Wen; Jonathan van Beek; Laura Kennedy; Marilyn McLeod; Elisabetta A Renzoni; George Bou-Gharios; Sarah Wilcox-Adelman; Paul F Goetinck; Mark Eastwood; Carol M Black; David J Abraham; Andrew Leask
Journal:  Am J Pathol       Date:  2005-12       Impact factor: 4.307

8.  Effect of topical basic fibroblast growth factor on the healing of chronic diabetic neuropathic ulcer of the foot. A pilot, randomized, double-blind, placebo-controlled study.

Authors:  J L Richard; C Parer-Richard; J P Daures; S Clouet; D Vannereau; J Bringer; M Rodier; C Jacob; M Comte-Bardonnet
Journal:  Diabetes Care       Date:  1995-01       Impact factor: 19.112

9.  Decreased macrophage number and activation lead to reduced lymphatic vessel formation and contribute to impaired diabetic wound healing.

Authors:  Kazuichi Maruyama; Jun Asai; Masaaki Ii; Tina Thorne; Douglas W Losordo; Patricia A D'Amore
Journal:  Am J Pathol       Date:  2007-04       Impact factor: 4.307

Review 10.  Growth factors and wound healing: biochemical properties of growth factors and their receptors.

Authors:  N T Bennett; G S Schultz
Journal:  Am J Surg       Date:  1993-06       Impact factor: 2.565

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  1 in total

1.  Intramuscular autologous blood therapy - a systematic review of controlled trials.

Authors:  Katja Oomen-Welke; Roman Huber
Journal:  BMC Complement Altern Med       Date:  2019-09-05       Impact factor: 3.659

  1 in total

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