| Literature DB >> 24526792 |
Mustafa Cetin1, Eftal Murat Bakirci2, Erkan Baysal3, Hakan Tasolar4, Mehmet Balli4, Musa Cakici4, Sabri Abus4, Erdal Akturk4, Sami Ozgul4.
Abstract
We investigated 2 hypotheses: (1) a relationship between platelet indices and stable coronary artery disease (CAD) and acute ST-segment elevation myocardial infarction (STEMI) and (2) a relationship between platelet indices on admission and thrombolysis outcomes in patients with STEMI. A total of 260 patients were enrolled. The white blood cell (WBC) and platelet distribution width (PDW) were found to be increased in patients with STEMI (P for both < .001). White blood cell and PDW were independent predictors of acute STEMI. Mean platelet volume (MPV) and PDW were significantly higher in the thrombolysis failure group than in the thrombolysis success group (9.9 ± 1.8 vs 9.2 ± 1.5 fL, P = .021 and 17.7 ± 1.0 vs 16.4 ± 2.1 fL, P < .001, respectively). Mean platelet volume and PDW were independent predictors of thrombolysis failure. Patients with acute STEMI had higher PDW than did patients with stable CAD. In addition, higher PDW and MPV seem to correlate with thrombolysis failure in patients with STEMI.Entities:
Keywords: coronary artery disease; fibrinolysis; mean platelet volume; myocardial infarction; platelet distribution width; thrombolysis
Mesh：
Year: 2014 PMID： 24526792 DOI： 10.1177/0003319713520068
Source DB: PubMed Journal: Angiology ISSN： 0003-3197 Impact factor: 3.619