Literature DB >> 2452648

High prevalence of serum antibodies to reverse transcriptase in HIV-1-infected individuals.

A L DeVico1, F D Veronese, S L Lee, R C Gallo, M G Sarngadharan.   

Abstract

The HIV immunoblot profiles of 700 HIV-antibody-positive sera were examined to determine the frequency of antibody reactivity with p66/p51, the reverse transcriptase of HIV. We report a remarkably high seroprevalence of antibodies to p66/p51, detected in 79% of the sera. Only gp41 is recognized more frequently in these assays. The level of anti-p66/p51 seroreactivity varies only slightly among the clinical stages of HIV infection.

Entities:  

Mesh：

Substances：

Year:  1988        PMID： 2452648     DOI： 10.1089/aid.1988.4.17

Source DB:  PubMed          Journal:  AIDS Res Hum Retroviruses        ISSN： 0889-2229            Impact factor:   2.205


  5 in total

1.  Cross-sectional study of reverse transcriptase-inhibiting antibody as a marker of acquired immune deficiency syndrome.

Authors:  M Advani; D T Imagawa; M H Lee; K Sano; F Morales; R T Mitsuyasu; R Detels
Journal:  J Clin Microbiol       Date:  1989-07       Impact factor: 5.948

2.  Monitoring human immunodeficiency virus type 1-infected patients by ratio of antibodies to gp41 and p24.

Authors:  G Schmidt; K Amiraian; H Frey; J Wethers; R W Stevens; D S Berns
Journal:  J Clin Microbiol       Date:  1989-05       Impact factor: 5.948

3.  Measurement of levels of human immunodeficiency virus type 1 reverse transcriptase (RT) and RT activity-blocking antibody in human serum by a new standardized colorimetric assay.

Authors:  R J Awad; G E Corrigan; D H Ekstrand; R Thorstensson; C F Källander; J S Gronowitz
Journal:  J Clin Microbiol       Date:  1997-05       Impact factor: 5.948

4.  Enzyme immunoassay using native envelope glycoprotein (gp160) for detection of human immunodeficiency virus type 1 antibodies.

Authors:  B C Nair; G Ford; V S Kalyanaraman; M Zafari; C Fang; M G Sarngadharan
Journal:  J Clin Microbiol       Date:  1994-06       Impact factor: 5.948

5.  Differentiation between human immunodeficiency virus type 1 (HIV-1) and HIV-2 isolates by nonradioisotopic reverse transcriptase-typing assay.

Authors:  T Urabe; K Sano; T Nakano; F Odawara; M H Lee; T Otake; S Okubo; M Hayami; H Misaki; M Baba
Journal:  J Clin Microbiol       Date:  1994-08       Impact factor: 5.948
  5 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.