Literature DB >> 2452385

Galanin selectively modulates 5-hydroxytryptamine 1A receptors in the rat ventral limbic cortex.

K Fuxe1, G von Euler, L F Agnati, S O Ogren.   

Abstract

The effects of galanin (10 nM) in vitro were analyzed on the binding characteristics of 5-hydroxytryptamine (5-HT) receptor subtypes in the ventral limbic cortex of the rat. It was found that galanin markedly decreased the Kd value of 5-HT1A binding, while there were no effects on the binding characteristics of the 5-HT1B or 5-HT2 radioligands. These results indicate that the existence of a selective intramembrane interaction between galanin receptors and 5-HT1A receptors in the rat ventral limbic cortex.

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Year:  1988        PMID： 2452385     DOI： 10.1016/0304-3940(88)90448-x

Source DB:  PubMed          Journal:  Neurosci Lett        ISSN： 0304-3940            Impact factor:   3.046


  11 in total

Review 1.  Central nervous system regulation of food intake and energy expenditure: role of galanin-mediated feeding behavior.

Authors:  Peng-Hua Fang; Mei Yu; Yin-Ping Ma; Jian Li; Yu-Mei Sui; Ming-Yi Shi
Journal:  Neurosci Bull       Date:  2011-12       Impact factor: 5.203

Review 2.  Intramembrane receptor-receptor interactions: a novel principle in molecular medicine.

Authors:  K Fuxe; M Canals; M Torvinen; D Marcellino; A Terasmaa; S Genedani; G Leo; D Guidolin; Z Diaz-Cabiale; A Rivera; L Lundstrom; U Langel; J Narvaez; S Tanganelli; C Lluis; S Ferré; A Woods; R Franco; L F Agnati
Journal:  J Neural Transm (Vienna)       Date:  2006-10-27       Impact factor: 3.575

Review 3.  Receptor-receptor interactions as an integrative mechanism in nerve cells.

Authors:  M Zoli; L F Agnati; P B Hedlund; X M Li; S Ferré; K Fuxe
Journal:  Mol Neurobiol       Date:  1993 Fall-Winter       Impact factor: 5.590

4.  GAL3 receptor KO mice exhibit an anxiety-like phenotype.

Authors:  Susanne M Brunner; Aitak Farzi; Felix Locker; Barbara S Holub; Meinrad Drexel; Florian Reichmann; Andreas A Lang; Johannes A Mayr; Jorge J Vilches; Xavier Navarro; Roland Lang; Günther Sperk; Peter Holzer; Barbara Kofler
Journal:  Proc Natl Acad Sci U S A       Date:  2014-04-29       Impact factor: 11.205

Review 5.  Galanin and its receptors in neurological disorders.

Authors:  Linda Lundström; Anna Elmquist; Tamas Bartfai; Ulo Langel
Journal:  Neuromolecular Med       Date:  2005       Impact factor: 3.843

Review 6.  Galanin receptor antagonists : a potential novel pharmacological treatment for mood disorders.

Authors:  Sven Ove Ogren; Eugenia Kuteeva; Tomas Hökfelt; Jan Kehr
Journal:  CNS Drugs       Date:  2006       Impact factor: 5.749

Review 7.  Dysfunctional Heteroreceptor Complexes as Novel Targets for the Treatment of Major Depressive and Anxiety Disorders.

Authors:  Miguel Pérez de la Mora; Dasiel O Borroto-Escuela; Minerva Crespo-Ramírez; José Del Carmen Rejón-Orantes; Daniel Alejandro Palacios-Lagunas; Magda K Martínez-Mata; Daniela Sánchez-Luna; Emiliano Tesoro-Cruz; Kjell Fuxe
Journal:  Cells       Date:  2022-06-02       Impact factor: 7.666

Review 8.  Understanding the Role of GPCR Heteroreceptor Complexes in Modulating the Brain Networks in Health and Disease.

Authors:  Dasiel O Borroto-Escuela; Jens Carlsson; Patricia Ambrogini; Manuel Narváez; Karolina Wydra; Alexander O Tarakanov; Xiang Li; Carmelo Millón; Luca Ferraro; Riccardo Cuppini; Sergio Tanganelli; Fang Liu; Malgorzata Filip; Zaida Diaz-Cabiale; Kjell Fuxe
Journal:  Front Cell Neurosci       Date:  2017-02-21       Impact factor: 5.505

9.  Existence of Brain 5-HT1A-5-HT2A Isoreceptor Complexes with Antagonistic Allosteric Receptor-Receptor Interactions Regulating 5-HT1A Receptor Recognition.

Authors:  Dasiel O Borroto-Escuela; Xiang Li; Alexander O Tarakanov; David Savelli; Manuel Narváez; Kirill Shumilov; Yuniesky Andrade-Talavera; Antonio Jimenez-Beristain; Bartosz Pomierny; Zaida Díaz-Cabiale; Riccardo Cuppini; Patrizia Ambrogini; Maria Lindskog; Kjell Fuxe
Journal:  ACS Omega       Date:  2017-08-22

10.  On the existence and function of galanin receptor heteromers in the central nervous system.

Authors:  Kjell Fuxe; Dasiel O Borroto-Escuela; Wilber Romero-Fernandez; Alexander O Tarakanov; Feliciano Calvo; Pere Garriga; Mercé Tena; Manuel Narvaez; Carmelo Millón; Concepción Parrado; Francisco Ciruela; Luigi F Agnati; José A Narvaez; Zaida Díaz-Cabiale
Journal:  Front Endocrinol (Lausanne)       Date:  2012-10-26       Impact factor: 5.555
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