Literature DB >> 24522940

Isolated limb infusion as a model to test new agents to treat metastatic melanoma.

Michael E Lidsky1, Paul J Speicher, Betty Jiang, Masahito Tsutsui, Douglas S Tyler.   

Abstract

The limb model of in-transit disease can expand our understanding of treating melanoma because of the ease of obtaining tissue biopsies for correlative studies and the availability of preclinical animal models that allow validation of novel therapeutic strategies. This review will focus on regional therapy for in-transit melanoma as a platform to investigate novel therapeutic approaches to improve regional disease control, and help us develop insights to more rationally design systemic therapy trials.
© 2013 Wiley Periodicals, Inc.

Entities:  

Keywords:  in-transit; isolated limb infusion; melanoma

Mesh：

Year:  2013        PMID： 24522940      PMCID： PMC5161101          DOI： 10.1002/jso.23502

Source DB:  PubMed          Journal:  J Surg Oncol        ISSN： 0022-4790            Impact factor:   3.454


  118 in total

1.  Depletion of glutathione in normal and malignant human cells in vivo by buthionine sulfoximine: clinical and biochemical results.

Authors:  P J O'Dwyer; T C Hamilton; R C Young; F P LaCreta; N Carp; K D Tew; K Padavic; R L Comis; R F Ozols
Journal:  J Natl Cancer Inst       Date:  1992-02-19       Impact factor: 13.506

Review 2.  Molecular pathways: hypoxia response in immune cells fighting or promoting cancer.

Authors:  Asis Palazón; Julián Aragonés; Aizea Morales-Kastresana; Manuel Ortiz de Landázuri; Ignacio Melero
Journal:  Clin Cancer Res       Date:  2011-12-28       Impact factor: 12.531

3.  B7-2 expression on tumor cells is important for the acquisition of cytotoxic T lymphocyte activity by spleen cells from low-dose-melphalan-treated MOPC-315 tumor bearers via a mechanism that requires either B7-1 or B7-2 expression on host antigen-presenting cells.

Authors:  D K Sojka; R N La Motte; M B Mokyr
Journal:  Cancer Immunol Immunother       Date:  2000-04       Impact factor: 6.968

4.  Role of DNA mismatch repair and p53 in signaling induction of apoptosis by alkylating agents.

Authors:  M J Hickman; L D Samson
Journal:  Proc Natl Acad Sci U S A       Date:  1999-09-14       Impact factor: 11.205

5.  Tumor antigen-specific CD8 T cells infiltrating the tumor express high levels of PD-1 and are functionally impaired.

Authors:  Mojgan Ahmadzadeh; Laura A Johnson; Bianca Heemskerk; John R Wunderlich; Mark E Dudley; Donald E White; Steven A Rosenberg
Journal:  Blood       Date:  2009-05-07       Impact factor: 22.113

6.  Modulation of resistance to regional chemotherapy in the extremity melanoma model.

Authors:  Elizabeth G Grubbs; Tomio Ueno; Omar Abdel-Wahab; Tsung-Yen Cheng; Scott K Pruitt; O Michael Colvin; Henry S Friedman; Douglas S Tyler
Journal:  Surgery       Date:  2004-08       Impact factor: 3.982

7.  Nitrogen mustard-DNA interaction in melphalan-resistant mammary carcinoma cells with elevated intracellular glutathione and glutathione-S-transferase activity.

Authors:  M A Alaoui-Jamali; L Panasci; G M Centurioni; R Schecter; S Lehnert; G Batist
Journal:  Cancer Chemother Pharmacol       Date:  1992       Impact factor: 3.333

8.  Acidosis plus melphalan induces nitric oxide-mediated tumor regression in an isolated limb perfusion human melanoma xenograft model.

Authors:  Scott T Kelley; Chandrakala Menon; Donald G Buerk; Todd W Bauer; Douglas L Fraker
Journal:  Surgery       Date:  2002-08       Impact factor: 3.982

9.  Treatment of patients with melanoma of the extremity using hyperthermic isolated limb perfusion with melphalan, tumor necrosis factor, and interferon gamma: results of a tumor necrosis factor dose-escalation study.

Authors:  D L Fraker; H R Alexander; M Andrich; S A Rosenberg
Journal:  J Clin Oncol       Date:  1996-02       Impact factor: 44.544

Review 10.  Angiogenesis in melanoma.

Authors:  Ganapati H Mahabeleshwar; Tatiana V Byzova
Journal:  Semin Oncol       Date:  2007-12       Impact factor: 4.929
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  3 in total

Review 1.  Progress with Recombinant Adeno-Associated Virus Vectors for Gene Therapy of Alpha-1 Antitrypsin Deficiency.

Authors:  Alisha M Gruntman; Terence R Flotte
Journal:  Hum Gene Ther Methods       Date:  2015-06       Impact factor: 2.396

Review 2.  The Role of Regional Therapies for in-Transit Melanoma in the Era of Improved Systemic Options.

Authors:  Emmanuel Gabriel; Joseph Skitzki
Journal:  Cancers (Basel)       Date:  2015-07-01       Impact factor: 6.639

Review 3.  Molecular Aspects of the Isolated Limb Infusion Procedure.

Authors:  Jüri Teras; Michael J Carr; Jonathan S Zager; Hidde M Kroon
Journal:  Biomedicines       Date:  2021-02-07
  3 in total

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