Literature DB >> 24522106

ReGAE 10: long-term visual acuity outcomes after acute primary angle closure.

Walter Andreatta1, Maged Nessim, Peter Nightingale, Peter Shah.   

Abstract

PURPOSE: The aim of this study was to identify the long-term visual acuity (VA) outcomes of eyes following an attack of acute primary angle closure in an urban UK population. PATIENTS AND METHODS: This was a retrospective observational case series of 134 consecutive eyes of 123 subjects presenting with acute primary angle closure to a supraregional tertiary referral unit in the United Kingdom over a period of 60 months. The VA in the affected eye was recorded at presentation 6 months after the acute event and at the final follow-up. In addition, causes of poor vision were documented as sociodemographic variables and surgical interventions. The main outcome measure was severe visual impairment (SVI). SVI was classified as VA<6/60 in the affected eye.
RESULTS: A total of 134 eyes of 123 subjects were assessed, 89 (72%) female and 34 (28%) male patients. The majority of the individuals were White Caucasians (78%), followed by Indian and Pakistani (14%), African Caribbean (4%), and Chinese (2.4%). The mean age was 67.3±11.9 years.During the period of follow-up, 44 (33%) eyes needed a cataract surgery, whereas 13 (10%) eyes underwent filtration surgery. Eight (6%) eyes had combined cataract and filtration surgery. The mean final follow-up period was 31.4±18.1 months. At this stage, 16 (12%) of the affected eyes had SVI. Glaucomatous optic neuropathy was responsible for SVI in 5/16 eyes, 1 eye had corneal decompensation, whereas 2/16 eyes were affected by central retinal vein occlusion. Other SVI causes were age-related macular degeneration (5/16) and cataract (3/16).
CONCLUSIONS: Sixteen (12%) eyes had SVI at the final follow-up. One third of SVI was secondary to GON.

Entities:  

Mesh:

Year:  2014        PMID: 24522106     DOI: 10.1097/IJG.0000000000000042

Source DB:  PubMed          Journal:  J Glaucoma        ISSN: 1057-0829            Impact factor:   2.503


  3 in total

1.  Selective Vulnerability of Specific Retinal Ganglion Cell Types and Synapses after Transient Ocular Hypertension.

Authors:  Yvonne Ou; Rebecca E Jo; Erik M Ullian; Rachel O L Wong; Luca Della Santina
Journal:  J Neurosci       Date:  2016-08-31       Impact factor: 6.167

2.  Long-term outcomes after acute primary angle closure in a White Caucasian population.

Authors:  Walter Andreatta; Ibrahim Elaroud; Peter Nightingale; Maged Nessim
Journal:  BMC Ophthalmol       Date:  2015-08-19       Impact factor: 2.209

3.  Mouse model of ocular hypertension with retinal ganglion cell degeneration.

Authors:  Ryo Mukai; Dong Ho Park; Yoko Okunuki; Eiichi Hasegawa; Garrett Klokman; Clifford B Kim; Anitha Krishnan; Meredith Gregory-Ksander; Deeba Husain; Joan W Miller; Kip M Connor
Journal:  PLoS One       Date:  2019-01-14       Impact factor: 3.240

  3 in total

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