Literature DB >> 2452126

Relationships between DNA and protein polymorphisms of apolipoprotein B.

A M Dunning1, M J Tikkanen, C Ehnholm, R Bütler, S E Humphries.   

Abstract

The associations between four restriction fragment length polymorphisms (RFLPs) of the gene for human apolipoprotein B (apo B) and five antigen group (Ag) protein-polymorphisms of apo B have been investigated in 24 unrelated Finnish individuals. In this sample a complete correlation exists between the EcoRI RFLP and the Ag(t/z) polymorphism. There is strong association between the alleles of the XbaI RFLP and Ag(c/g) and a weaker one of the same XbaI site with Ag(x/y). Linkage disequilibrium is observed between the PvuII RFLP and the Ag(a1/d) polymorphism. These associations confirm that the Ag variants are true protein sequence polymorphisms of apo B.

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Year:  1988        PMID： 2452126     DOI： 10.1007/bf00291728

Source DB:  PubMed          Journal:  Hum Genet        ISSN： 0340-6717            Impact factor:   4.132


  29 in total

1.  Two DNA restriction fragment length polymorphisms associated with Ag(t/z) and Ag(g/c) antigenic sites of human apolipoprotein B.

Authors:  Y H Ma; V N Schumaker; R Butler; R S Sparkes
Journal:  Arteriosclerosis       Date:  1987 May-Jun

2.  Analysis of human Y-chromosome-specific reiterated DNA in chromosome variants.

Authors:  L M Kunkel; K D Smith; S H Boyer; D S Borgaonkar; S S Wachtel; O J Miller; W R Breg; H W Jones; J M Rary
Journal:  Proc Natl Acad Sci U S A       Date:  1977-03       Impact factor: 11.205

3.  Contribution to the inheritance of the Ag groups. A population genetic study.

Authors:  R Bütler; E Brunner; G Morganti
Journal:  Vox Sang       Date:  1974       Impact factor: 2.144

4.  Isolation of a cDNA clone encoding the amino-terminal region of human apolipoprotein B.

Authors:  A A Protter; D A Hardman; J W Schilling; J Miller; V Appleby; G C Chen; S W Kirsher; G McEnroe; J P Kane
Journal:  Proc Natl Acad Sci U S A       Date:  1986-03       Impact factor: 11.205

5.  Nonuniform recombination within the human beta-globin gene cluster.

Authors:  A Chakravarti; K H Buetow; S E Antonarakis; P G Waber; C D Boehm; H H Kazazian
Journal:  Am J Hum Genet       Date:  1984-11       Impact factor: 11.025

6.  "A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity". Addendum.

Authors:  A P Feinberg; B Vogelstein
Journal:  Anal Biochem       Date:  1984-02       Impact factor: 3.365

7.  Comparative studies on anti-Ag sera in immunodiffusion and in passive hemagglutination methods.

Authors:  R Bütler; E Brunner; A Vierucci; G Morganti
Journal:  Vox Sang       Date:  1967-10       Impact factor: 2.144

8.  Genetic variation in serum low density lipoproteins and lipid levels in man.

Authors:  K Berg; C Hames; G Dahlén; M H Frick; I Krishan
Journal:  Proc Natl Acad Sci U S A       Date:  1976-03       Impact factor: 11.205

9.  Detection of human apolipoprotein B polymorphic species with one monoclonal antibody (BIP 45) against low density lipoprotein. Influence of this polymorphism on lipid levels and coronary artery stenosis.

Authors:  P Duriez; N Vu Dac; M Koffigan; P Puchois; C Demarquilly; C Fievet; P Fievet; I Luyeye; J M Bard; J L Fourrier
Journal:  Atherosclerosis       Date:  1987-07       Impact factor: 5.162

10.  Structure of the human apolipoprotein B gene.

Authors:  B D Blackhart; E M Ludwig; V R Pierotti; L Caiati; M A Onasch; S C Wallis; L Powell; R Pease; T J Knott; M L Chu
Journal:  J Biol Chem       Date:  1986-11-25       Impact factor: 5.157
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  7 in total

1.  Role of candidate genes in the lipid responses to intensified treatment in Type 2 diabetes.

Authors:  O Ukkola; J Salonen; Y Antero Kesäniemi
Journal:  J Endocrinol Invest       Date:  2005-11       Impact factor: 4.256

2.  A worldwide population study of the Ag-system haplotypes, a genetic polymorphism of human low-density lipoprotein.

Authors:  G Breguet; R Bütler; E Bütler-Brunner; A Sanchez-Mazas
Journal:  Am J Hum Genet       Date:  1990-03       Impact factor: 11.025

3.  Apolipoprotein B amino acid 3611 substitution from arginine to glutamine creates the Ag (h/i) epitope: the polymorphism is not associated with differences in serum cholesterol and apolipoprotein B levels.

Authors:  C F Xu; N Nanjee; M J Tikkanen; J K Huttunen; P Pietinen; R Bütler; F Angelico; M Del Ben; B Mazzarella; R Antonio
Journal:  Hum Genet       Date:  1989-07       Impact factor: 4.132

4.  Genetic polymorphism of the apolipoprotein B gene locus influences serum LDL cholesterol level in familial hypercholesterolemia.

Authors:  K Aalto-Setälä; H Gylling; E Helve; P Kovanen; T A Miettinen; H Turtola; K Kontula
Journal:  Hum Genet       Date:  1989-07       Impact factor: 4.132

5.  Two amino acid substitutions in apolipoprotein B are in complete allelic association with the antigen group (x/y) polymorphism: evidence for little recombination in the 3' end of the human gene.

Authors:  A M Dunning; H H Renges; C F Xu; R Peacock; R Brasseur; G Laxer; M J Tikkanen; R Bütler; N Saha; A Hamsten
Journal:  Am J Hum Genet       Date:  1992-01       Impact factor: 11.025

Review 6.  The apolipoprotein multigene family: structure, expression, evolution, and molecular genetics.

Authors:  L Chan
Journal:  Klin Wochenschr       Date:  1989-02-15

7.  Apolipoprotein B-100 XbaI gene polymorphism in gallbladder cancer.

Authors:  Mahendra Kumar Singh; Udai Bhan Pandey; Uday Chand Ghoshal; Itha Srivenu; Vinay Kumar Kapoor; Gourdas Choudhuri; Balraj Mittal
Journal:  Hum Genet       Date:  2003-11-14       Impact factor: 4.132
  7 in total

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