| Literature DB >> 24518920 |
Oscar S H Chan1, Roger K C Ngan2.
Abstract
The stage IVC nasopharyngeal carcinoma is a catch-all entity covering minute solitary metastasis to bulky disseminated disease. Prognosis varies greatly within this stage group. A subset of patients with oligometastases may benefit from aggressive local ablative therapy. Meanwhile, in multiple metastatic diseases, customizing conventional cytotoxics basing on individual tumor characteristics and previous chemotherapy responses can be a new direction to improve therapeutic results. Prognostic models built on clinical features and genomic profiles can be utilized to stratify different risk groups and tailor therapy schemes.Entities:
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Year: 2014 PMID： 24518920 DOI： 10.1016/j.oraloncology.2014.01.004
Source DB: PubMed Journal: Oral Oncol ISSN： 1368-8375 Impact factor: 5.337