Literature DB >> 24518415

On the other hand: including left-handers in cognitive neuroscience and neurogenetics.

Roel M Willems1, Lise Van der Haegen2, Simon E Fisher1, Clyde Francks1.   

Abstract

Left-handers are often excluded from study cohorts in neuroscience and neurogenetics in order to reduce variance in the data. However, recent investigations have shown that the inclusion or targeted recruitment of left-handers can be informative in studies on a range of topics, such as cerebral lateralization and the genetic underpinning of asymmetrical brain development. Left-handed individuals represent a substantial portion of the human population and therefore left-handedness falls within the normal range of human diversity; thus, it is important to account for this variation in our understanding of brain functioning. We call for neuroscientists and neurogeneticists to recognize the potential of studying this often-discarded group of research subjects.

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Year:  2014        PMID: 24518415     DOI: 10.1038/nrn3679

Source DB:  PubMed          Journal:  Nat Rev Neurosci        ISSN: 1471-003X            Impact factor:   34.870


  122 in total

1.  Asymmetry of fetal cerebral hemispheres: in utero ultrasound study.

Authors:  R Hering-Hanit; R Achiron; S Lipitz; A Achiron
Journal:  Arch Dis Child Fetal Neonatal Ed       Date:  2001-11       Impact factor: 5.747

2.  Anatomical left-right asymmetry of language-related temporal cortex is different in left- and right-handers.

Authors:  H Steinmetz; J Volkmann; L Jäncke; H J Freund
Journal:  Ann Neurol       Date:  1991-03       Impact factor: 10.422

3.  Body-specific representations of action verbs: neural evidence from right- and left-handers.

Authors:  Roel M Willems; Peter Hagoort; Daniel Casasanto
Journal:  Psychol Sci       Date:  2009-11-23

4.  Footedness is a better predictor of language lateralisation than handedness.

Authors:  L J Elias; M P Bryden
Journal:  Laterality       Date:  1998-01

Review 5.  Neural evidence for the interplay between language, gesture, and action: a review.

Authors:  Roel M Willems; Peter Hagoort
Journal:  Brain Lang       Date:  2007-04-09       Impact factor: 2.381

6.  Effect of familial sinistrality on planum temporale surface and brain tissue asymmetries.

Authors:  Nathalie Tzourio-Mazoyer; Gregory Simon; Fabrice Crivello; Gael Jobard; Laure Zago; Guy Perchey; Pierre-Yves Hervé; Marc Joliot; Laurent Petit; Emmanuel Mellet; Bernard Mazoyer
Journal:  Cereb Cortex       Date:  2009-10-21       Impact factor: 5.357

7.  Embodied cognition: taking the next step.

Authors:  Roel M Willems; Jolien C Francken
Journal:  Front Psychol       Date:  2012-12-28

8.  Impact of brain-derived neurotrophic factor Val66Met polymorphism on cortical thickness and voxel-based morphometry in healthy Chinese young adults.

Authors:  Xuejuan Yang; Peng Liu; Jinbo Sun; Guihong Wang; Fang Zeng; Kai Yuan; Jixin Liu; Minghao Dong; Karen M von Deneen; Wei Qin; Jie Tian
Journal:  PLoS One       Date:  2012-06-13       Impact factor: 3.240

9.  Common variants in left/right asymmetry genes and pathways are associated with relative hand skill.

Authors:  William M Brandler; Andrew P Morris; David M Evans; Thomas S Scerri; John P Kemp; Nicholas J Timpson; Beate St Pourcain; George Davey Smith; Susan M Ring; John Stein; Anthony P Monaco; Joel B Talcott; Simon E Fisher; Caleb Webber; Silvia Paracchini
Journal:  PLoS Genet       Date:  2013-09-12       Impact factor: 5.917

10.  Body-specific motor imagery of hand actions: neural evidence from right- and left-handers.

Authors:  Roel M Willems; Ivan Toni; Peter Hagoort; Daniel Casasanto
Journal:  Front Hum Neurosci       Date:  2009-11-10       Impact factor: 3.169

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  63 in total

1.  Left-Right Axis Differentiation and Functional Lateralization: a Haplotype in the Methyltransferase Encoding Gene SETDB2 Might Mediate Handedness in Healthy Adults.

Authors:  Sebastian Ocklenburg; Larissa Arning; Wanda M Gerding; Jan G Hengstler; Jörg T Epplen; Onur Güntürkün; Christian Beste; Denis A Akkad
Journal:  Mol Neurobiol       Date:  2015-11-16       Impact factor: 5.590

2.  Neural Substrates of Processing Anger in Language: Contributions of Prosody and Semantics.

Authors:  Brian C Castelluccio; Emily B Myers; Jillian M Schuh; Inge-Marie Eigsti
Journal:  J Psycholinguist Res       Date:  2016-12

Review 3.  Elevated Levels of Atypical Handedness in Autism: Meta-Analyses.

Authors:  Paraskevi Markou; Banu Ahtam; Marietta Papadatou-Pastou
Journal:  Neuropsychol Rev       Date:  2017-07-23       Impact factor: 7.444

4.  Dynamic brain network configurations during rest and an attention task with frequent occurrence of mind wandering.

Authors:  Ekaterina Denkova; Jason S Nomi; Lucina Q Uddin; Amishi P Jha
Journal:  Hum Brain Mapp       Date:  2019-08-04       Impact factor: 5.038

5.  Visuospatial Asymmetries Arise from Differences in the Onset Time of Perceptual Evidence Accumulation.

Authors:  Daniel P Newman; Gerard M Loughnane; Simon P Kelly; Redmond G O'Connell; Mark A Bellgrove
Journal:  J Neurosci       Date:  2017-02-27       Impact factor: 6.167

6.  Non-right handed primary progressive apraxia of speech.

Authors:  Hugo Botha; Joseph R Duffy; Jennifer L Whitwell; Edythe A Strand; Mary M Machulda; Anthony J Spychalla; Nirubol Tosakulwong; Matthew L Senjem; David S Knopman; Ronald C Petersen; Clifford R Jack; Val J Lowe; Keith A Josephs
Journal:  J Neurol Sci       Date:  2018-05-07       Impact factor: 3.181

Review 7.  What can atypical language hemispheric specialization tell us about cognitive functions?

Authors:  Qing Cai; Lise Van der Haegen
Journal:  Neurosci Bull       Date:  2015-03-31       Impact factor: 5.203

8.  Spinal and Cerebral Integration of Noxious Inputs in Left-handed Individuals.

Authors:  Stéphane Northon; Zoha Deldar; Mathieu Piché
Journal:  Brain Topogr       Date:  2021-08-02       Impact factor: 3.020

9.  Motor behavior reflects reduced hemispheric asymmetry in the psychosis risk period.

Authors:  Derek J Dean; Joseph M Orr; Raeana E Newberry; Vijay A Mittal
Journal:  Schizophr Res       Date:  2015-10-20       Impact factor: 4.939

10.  Structural Variability within Frontoparietal Networks and Individual Differences in Attentional Functions: An Approach Using the Theory of Visual Attention.

Authors:  Magdalena Chechlacz; Celine R Gillebert; Signe A Vangkilde; Anders Petersen; Glyn W Humphreys
Journal:  J Neurosci       Date:  2015-07-29       Impact factor: 6.167

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