BACKGROUND: Multicentre clinical trials are challenged by high administrative burden, data management pitfalls and costs. This leads to a reduced enthusiasm and commitment of the physicians involved and thus to a reluctance in conducting multicentre clinical trials. OBJECTIVE: The purpose of this study was to develop a web-based open source platform to support a multi-centre clinical trial. METHODS: We developed on Drupal, an open source software distributed under the terms of the General Public License, a web-based, multi-centre clinical trial management system with the design science research approach. RESULTS: This system was evaluated by user-testing and well supported several completed and on-going clinical trials and is available for free download. CONCLUSION: Open source clinical trial management systems are capable in supporting multi-centre clinical trials by enhancing efficiency, quality of data management and collaboration.
BACKGROUND: Multicentre clinical trials are challenged by high administrative burden, data management pitfalls and costs. This leads to a reduced enthusiasm and commitment of the physicians involved and thus to a reluctance in conducting multicentre clinical trials. OBJECTIVE: The purpose of this study was to develop a web-based open source platform to support a multi-centre clinical trial. METHODS: We developed on Drupal, an open source software distributed under the terms of the General Public License, a web-based, multi-centre clinical trial management system with the design science research approach. RESULTS: This system was evaluated by user-testing and well supported several completed and on-going clinical trials and is available for free download. CONCLUSION: Open source clinical trial management systems are capable in supporting multi-centre clinical trials by enhancing efficiency, quality of data management and collaboration.
Authors: Dimitri Aristotle Raptis; Thomas Hanna; Nikolaos Machairas; Timothy Owen; Daniel Davies; Giuseppe Kito Fusai Journal: In Vivo Date: 2021 Mar-Apr Impact factor: 2.155
Authors: Grzegorz Zuk; Katharina B Reinisch; Dimitri A Raptis; Sonia Fertsch; Merlin Guggenheim; Adrian F Palma Journal: Interact J Med Res Date: 2017-06-22
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