BACKGROUND: A rhesus macaque developed chronic anemia, lymphocytic leukocytopenia, fever, and anorexia while immunodeficient following inoculation with a simian-human immunodeficiency virus. METHODS: A complete blood count, peripheral blood smear, polymerase chain reaction and gene sequence were performed. RESULTS: Blood smears demonstrated persistent intraerythrocytic piroplasms with rare Maltese cross forms. Babesia microti-like protozoa were confirmed by polymerase chain reaction and sequencing of the 18S ribosomal RNA gene. CONCLUSION: With continued use of non-human primates as models for human diseases, infection and complications from babesiosis should be monitored.
BACKGROUND: A rhesus macaque developed chronic anemia, lymphocytic leukocytopenia, fever, and anorexia while immunodeficient following inoculation with a simian-human immunodeficiency virus. METHODS: A complete blood count, peripheral blood smear, polymerase chain reaction and gene sequence were performed. RESULTS: Blood smears demonstrated persistent intraerythrocytic piroplasms with rare Maltese cross forms. Babesia microti-like protozoa were confirmed by polymerase chain reaction and sequencing of the 18S ribosomal RNA gene. CONCLUSION: With continued use of non-human primates as models for human diseases, infection and complications from babesiosis should be monitored.
Authors: Jessica Kenney; Rachel Singer; Nina Derby; Meropi Aravantinou; Ciby J Abraham; Radhika Menon; Samantha Seidor; Shimin Zhang; Agegnehu Gettie; James Blanchard; Michael Piatak; Jeffrey D Lifson; José A Fernández-Romero; Thomas M Zydowsky; Melissa Robbiani Journal: AIDS Res Hum Retroviruses Date: 2012-07-30 Impact factor: 2.205
Authors: Peter J Krause; Benjamin E Gewurz; David Hill; Francisco M Marty; Edouard Vannier; Ivo M Foppa; Richard R Furman; Ellen Neuhaus; Gail Skowron; Shaili Gupta; Carlo McCalla; Edward L Pesanti; Mary Young; Donald Heiman; Gunther Hsue; Jeffrey A Gelfand; Gary P Wormser; John Dickason; Frank J Bia; Barry Hartman; Sam R Telford; Diane Christianson; Kenneth Dardick; Morton Coleman; Jennifer E Girotto; Andrew Spielman Journal: Clin Infect Dis Date: 2008-02-01 Impact factor: 9.079