Literature DB >> 2451491

Human immunodeficiency virus replication in human brain cells. Brief report.

A Srinivasan1, D Dorsett, D York, C Bohan, R Anand.   

Abstract

Human immunodeficiency virus (HIV), the etiologic agent of AIDS, was found to infect and replicate in human brain cells. The extent of HIV replication was minimal in human brain-derived cells in comparison to T4 lymphoid cells. These results suggest that direct infection of glial/neuronal cells by HIV may contribute to the CNS dysfunction frequently observed in HIV infected individuals.

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Year:  1988        PMID： 2451491     DOI： 10.1007/bf01311031

Source DB:  PubMed          Journal:  Arch Virol        ISSN： 0304-8608            Impact factor:   2.574


  28 in total

1.  AIDS retrovirus (ARV-2) clone replicates in transfected human and animal fibroblasts.

Authors:  J A Levy; C Cheng-Mayer; D Dina; P A Luciw
Journal:  Science       Date:  1986-05-23       Impact factor: 47.728

2.  Production of acquired immunodeficiency syndrome-associated retrovirus in human and nonhuman cells transfected with an infectious molecular clone.

Authors:  A Adachi; H E Gendelman; S Koenig; T Folks; R Willey; A Rabson; M A Martin
Journal:  J Virol       Date:  1986-08       Impact factor: 5.103

3.  Immunohistochemical identification of HTLV-III antigen in brains of patients with AIDS.

Authors:  D H Gabuzda; D D Ho; S M de la Monte; M S Hirsch; T R Rota; R A Sobel
Journal:  Ann Neurol       Date:  1986-09       Impact factor: 10.422

4.  Non-cytocidal natural variants of human immunodeficiency virus isolated from AIDS patients with neurological disorders.

Authors:  R Anand; F Siegal; C Reed; T Cheung; S Forlenza; J Moore
Journal:  Lancet       Date:  1987-08-01       Impact factor: 79.321

5.  Molecular characterization of human immunodeficiency virus from Zaire: nucleotide sequence analysis identifies conserved and variable domains in the envelope gene.

Authors:  A Srinivasan; R Anand; D York; P Ranganathan; P Feorino; G Schochetman; J Curran; V S Kalyanaraman; P A Luciw; R Sanchez-Pescador
Journal:  Gene       Date:  1987       Impact factor: 3.688

6.  Susceptibility of human glial cells to infection with human immunodeficiency virus (HIV).

Authors:  S Dewhurst; J Bresser; M Stevenson; K Sakai; M J Evinger-Hodges; D J Volsky
Journal:  FEBS Lett       Date:  1987-03-09       Impact factor: 4.124

7.  The CD4 (T4) antigen is an essential component of the receptor for the AIDS retrovirus.

Authors:  A G Dalgleish; P C Beverley; P R Clapham; D H Crawford; M F Greaves; R A Weiss
Journal:  Nature       Date:  1984 Dec 20-1985 Jan 2       Impact factor: 49.962

8.  Isolation of HTLV-III from cerebrospinal fluid and neural tissues of patients with neurologic syndromes related to the acquired immunodeficiency syndrome.

Authors:  D D Ho; T R Rota; R T Schooley; J C Kaplan; J D Allan; J E Groopman; L Resnick; D Felsenstein; C A Andrews; M S Hirsch
Journal:  N Engl J Med       Date:  1985-12-12       Impact factor: 91.245

9.  Frequent detection and isolation of cytopathic retroviruses (HTLV-III) from patients with AIDS and at risk for AIDS.

Authors:  R C Gallo; S Z Salahuddin; M Popovic; G M Shearer; M Kaplan; B F Haynes; T J Palker; R Redfield; J Oleske; B Safai
Journal:  Science       Date:  1984-05-04       Impact factor: 47.728
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  7 in total

1.  A mechanism of restricted human immunodeficiency virus type 1 expression in human glial cells.

Authors:  M Shahabuddin; G Bentsman; B Volsky; I Rodriguez; D J Volsky
Journal:  J Virol       Date:  1996-11       Impact factor: 5.103

2.  Infection of human fetal dorsal root ganglion glial cells with human immunodeficiency virus type 1 involves an entry mechanism independent of the CD4 T4A epitope.

Authors:  C Kunsch; H T Hartle; B Wigdahl
Journal:  J Virol       Date:  1989-12       Impact factor: 5.103

3.  Highly productive infection with pseudotyped human immunodeficiency virus type 1 (HIV-1) indicates no intracellular restrictions to HIV-1 replication in primary human astrocytes.

Authors:  M Canki; J N Thai; W Chao; A Ghorpade; M J Potash; D J Volsky
Journal:  J Virol       Date:  2001-09       Impact factor: 5.103

4.  Infection of brain microglial cells by human immunodeficiency virus type 1 is CD4 dependent.

Authors:  C A Jordan; B A Watkins; C Kufta; M Dubois-Dalcq
Journal:  J Virol       Date:  1991-02       Impact factor: 5.103

5.  Identification of human immunodeficiency virus envelope gene sequences influencing viral entry into CD4-positive HeLa cells, T-leukemia cells, and macrophages.

Authors:  B Chesebro; J Nishio; S Perryman; A Cann; W O'Brien; I S Chen; K Wehrly
Journal:  J Virol       Date:  1991-11       Impact factor: 5.103

6.  Failure of human immunodeficiency virus entry and infection in CD4-positive human brain and skin cells.

Authors:  B Chesebro; R Buller; J Portis; K Wehrly
Journal:  J Virol       Date:  1990-01       Impact factor: 5.103

7.  CD4-independent, productive infection of a neuronal cell line by human immunodeficiency virus type 1.

Authors:  X L Li; T Moudgil; H V Vinters; D D Ho
Journal:  J Virol       Date:  1990-03       Impact factor: 5.103
  7 in total

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