Shyalle K Kahawita1, Robert J Casson2. 1. South Australian Institute of Ophthalmology, Royal Adelaide Hospital, Adelaide, South Australia, Australia. 2. South Australian Institute of Ophthalmology, Royal Adelaide Hospital, Adelaide, South Australia, Australia. Electronic address: s.kahawita@gmail.com.
Abstract
OBJECTIVE: The aim of this review was to evaluate the evidence for an association between Aspirin use and early age-related macular degeneration (ARMD). METHODS: A literature search was performed in 5 databases with no restrictions on language or date of publication. Four studies involving 10292 individuals examining the association between aspirin and ARMD met the inclusion criteria. Meta-analysis was carried out by Cochrane Collaboration Review Manager 5.2 software (Cochrane Collaboration, Copenhagen, Denmark). RESULTS: The pooled odd ratios showed that Aspirin use was associated with early ARMD (pooled odds ratio 1.43, 95% CI 1.09-1.88). CONCLUSIONS: There is a small but statistically significant association between Aspirin use and early ARMD, which may warrant further investigation. Crown
OBJECTIVE: The aim of this review was to evaluate the evidence for an association between Aspirin use and early age-related macular degeneration (ARMD). METHODS: A literature search was performed in 5 databases with no restrictions on language or date of publication. Four studies involving 10292 individuals examining the association between aspirin and ARMD met the inclusion criteria. Meta-analysis was carried out by Cochrane Collaboration Review Manager 5.2 software (Cochrane Collaboration, Copenhagen, Denmark). RESULTS: The pooled odd ratios showed that Aspirin use was associated with early ARMD (pooled odds ratio 1.43, 95% CI 1.09-1.88). CONCLUSIONS: There is a small but statistically significant association between Aspirin use and early ARMD, which may warrant further investigation. Crown
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