| Literature DB >> 24513265 |
Qianjun Zhou1, John Facciponte2, Min Jin3, Qiang Shen4, Qiang Lin5.
Abstract
Humanized mouse models have been developed and utilized in cancer research for decades. Newly developed combined immunodeficient NOD-SCID-IL2rg–/– mice are more permissive for human cells and tissue engraftment. In this review, we discuss the use of NOD-SCID-IL2rg(–/–) mice as a preclinical tool in cancer research and its potential use for individualized cancer therapies.Entities:
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Year: 2014 PMID: 24513265 DOI: 10.1016/j.canlet.2013.10.015
Source DB: PubMed Journal: Cancer Lett ISSN: 0304-3835 Impact factor: 8.679