Literature DB >> 24512987

Skin reducing mastectomy and immediate reconstruction: the effect of radiotherapy on complications and patient reported outcomes.

V Korwar1, J Skillman2, P Matey2.   

Abstract

AIM: Skin reducing mastectomy, dermal sling and immediate implant reconstruction (SRMIR) is an emerging technique where, de-epithelialised inferior skin flap sutured to pectoralis major provides vascularised, dermal sling for the implant. We aimed to assess patient satisfaction following SRMIR and determine if radiotherapy affected patient reported outcomes.
METHOD: A prospective database of women undergoing SRMIR was analysed. SRMIR was performed in 92 women (116 breasts). Radiotherapy was received by 45 women and it was not required in 47 women. Forty eight women had contralateral surgery: 21 breast reduction/mastopexy, 1 augmentation, 26 mastectomy/reconstruction. A validated breast evaluation questionnaire provided patient reported outcomes.
RESULTS: Median follow up was 20 months. Early complications were similar in both groups, but those in the radiotherapy group had a higher incidence of implant loss (6/45 = 13% vs 1/47 = 2%; p = 0.06) and grade III/IV capsular contracture (11/45 = 24% vs 6/47 = 13%; p = 0.20). The outcome questionnaire was sent to 83 women who were disease free and had retained their implants. Sixty three women responded (76%). Patient reported satisfaction was high, with or without radiotherapy. Women receiving radiotherapy gave lower scores, but it was statistically significant only for general appearance and symmetry.
CONCLUSIONS: Although complications after radiotherapy are higher in patients who had SRMIR, the majority of women who retained their implant are highly satisfied with their reconstruction. Majority of these patients were happy to recommend SRMIR procedure to their friend.
Copyright © 2014 Elsevier Ltd. All rights reserved.

Entities:  

Keywords:  Breast cancer; Breast implant; Breast reconstruction; Dermal sling; Radiotherapy; Single stage breast reconstruction; Skin reducing mastectomy

Mesh:

Year:  2014        PMID: 24512987     DOI: 10.1016/j.ejso.2014.01.003

Source DB:  PubMed          Journal:  Eur J Surg Oncol        ISSN: 0748-7983            Impact factor:   4.424


  5 in total

1.  Factors influencing the decision to pursue immediate breast reconstruction after mastectomy for breast cancer.

Authors:  Mariska Weenk; Philipp Wunschel; Erwin Heine; Luc J Strobbe
Journal:  Gland Surg       Date:  2017-02

2.  Nipple-Sparing Mastectomy and Immediate Implant-Based Reconstruction with or Without Skin Reduction in Patients with Large Ptotic Breasts: A Case-Matched Analysis.

Authors:  Sukru Yazar; Fuat Baris Bengur; Altug Altinkaya; Halil Kara; Cihan Uras
Journal:  Aesthetic Plast Surg       Date:  2020-10-23       Impact factor: 2.326

3.  Skin-reducing mastectomy and immediate breast reconstruction in patients with macromastia.

Authors:  Roy De Vita; Marcello Pozzi; Giovanni Zoccali; Maurizio Costantini; Pierpaolo Gullo; Ernesto Maria Buccheri; Antonio Varanese
Journal:  J Exp Clin Cancer Res       Date:  2015-10-14

4.  The satisfaction of patients with breast cancer undergone immediate reconstruction with implant and the effect of radiotherapy.

Authors:  Ayse Y Altinok; Nuran Bese; Halil Kara; Sukru Yazar; Cihan Unal
Journal:  Contemp Oncol (Pozn)       Date:  2018-04-03

5.  Therapeutic Reversal of Radiotherapy Injury to Pro-fibrotic Dysfunctional Fibroblasts In Vitro Using Adipose-derived Stem Cells.

Authors:  Lipi Shukla; Rodney Luwor; Matthew E Ritchie; Shiva Akbarzadeh; Hong-Jian Zhu; Wayne Morrison; Tara Karnezis; Ramin Shayan
Journal:  Plast Reconstr Surg Glob Open       Date:  2020-03-25
  5 in total

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