BACKGROUND: Migraine is a common primary headache disorder occurring predominantly in a young, relatively healthy population. RESULTS: There is a growing literature on associations between migraine, especially migraine with aura, and ischemic stroke as well as other vascular events. Migraine as a risk factor for vascular disease and connections between migraine and endothelial, structural, and genetic risk are reviewed. CONCLUSION: There may be an interaction between endothelial dysfunction and cortical spreading depression affecting risk. Patient education and treatment of modifiable risk factors may decrease future vascular events.
BACKGROUND:Migraine is a common primary headache disorder occurring predominantly in a young, relatively healthy population. RESULTS: There is a growing literature on associations between migraine, especially migraine with aura, and ischemic stroke as well as other vascular events. Migraine as a risk factor for vascular disease and connections between migraine and endothelial, structural, and genetic risk are reviewed. CONCLUSION: There may be an interaction between endothelial dysfunction and cortical spreading depression affecting risk. Patient education and treatment of modifiable risk factors may decrease future vascular events.
Authors: David Kudrow; Julio Pascual; Paul K Winner; David W Dodick; Stewart J Tepper; Uwe Reuter; Frank Hong; Jan Klatt; Feng Zhang; Sunfa Cheng; Hernan Picard; Osa Eisele; Julie Wang; Jonathan N Latham; Daniel D Mikol Journal: Neurology Date: 2019-12-18 Impact factor: 9.910
Authors: Süleyman Demircan; Mustafa Ataş; Sevgi Arık Yüksel; Melek D Ulusoy; İsa Yuvacı; Hasan Basri Arifoğlu; Burhan Başkan; Gökmen Zararsız Journal: J Ophthalmol Date: 2015-02-12 Impact factor: 1.909