Literature DB >> 24512086

Sleep disorders in cirrhotics; how can we detect ?

Genco Gencdal1, Fulya Gunsar, Cenk E Meral, Esin Salman, Berna Gürsel, Nevin Oruç, Zeki Karasu, Galip Ersöz, Ulus Salih Akarca.   

Abstract

BACKGROUND & AIMS: Sleep disorders (SDs) are common in cirrhotics and are often associated with hepatic encephalopathy. SDs negatively affect patients' daily activities and work efficiency. For this reason, early diagnosis is important. The methods used for diagnosis of SDs are not practical and need longer periods of application and evaluation. In this study, we aimed to investigate sleep disorders and related clinical parameters in cirrhosis and also wanted to investigate the using of Sleep Timing and Sleep Quality Screening questionnaire (STSQS), a simple form with a short application time, for diagnosis of SDs and its correlation with Pittsburg Sleep Quality Index (PSQI) form.
METHODS: Cirrhotic patients and age-matched healthy volunteers were enrolled. Patients were excluded from this study if they had neuropsychiatric disease or used excessive alcohol or drugs known to affect sleep. Both groups completed validated Turkish form of PSQI and STSQS. SD was defined as PSQI score (0-21) of >5 or STSQS ≥5.
RESULTS: One hundred and thirty-one cirrhotic patients and 18 healthy volunteers were enrolled. SDs in cirrhotics and control group were detected 56.5% and 27.8% by PSQI, 49.6% and 16.7% by STSQS respectively. SDs are the most frequent in the Child C patients, and the least frequent in the Child A patients (P > 0.05). No correlation was found between the MELD score and SDs. SDs were more common in cirrhotic patients with hypoalbuminaemia and low haemoglobin levels. In addition, the patients with decompensated cirrhosis had more frequently SDs than the patients with compensated cirrhosis. In the patient group, sleep latency and total sleep time, sleep parameters were correlated with SDs. STSQS had statistical significant correlation with PSQI for diagnosis of SDs.
CONCLUSION: SDs are common in cirrhotics and STSQS could be an appropriate and practical method for diagnosis of SDS in these patients. We can use it in cirrhotic patients at outpatient clinics.
© 2014 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

Entities:  

Keywords:  PSQI; STSQS; cirrhosis; sleep; sleep disorders

Mesh:

Year:  2014        PMID: 24512086     DOI: 10.1111/liv.12485

Source DB:  PubMed          Journal:  Liver Int        ISSN: 1478-3223            Impact factor:   5.828


  7 in total

1.  Glucose fluctuations reduce quality of sleep and of life in patients with liver cirrhosis.

Authors:  Masafumi Haraguchi; Hisamitsu Miyaaki; Tatsuki Ichikawa; Hidetaka Shibata; Takuya Honda; Eisuke Ozawa; Satoshi Miuma; Naota Taura; Fuminao Takeshima; Kazuhiko Nakao
Journal:  Hepatol Int       Date:  2016-09-13       Impact factor: 6.047

2.  Health related management plans improve sleep disorders of patients with chronic liver disease.

Authors:  Chunzi Liu; Hui Xie; Xin Zhang; Yanbo Yu; Xiaoning Zhang; Yanyan Sun; Lin Zhou; Beibei Su; Huaming Wang
Journal:  Int J Clin Exp Med       Date:  2015-06-15

Review 3.  Sleep disturbances in patients with liver cirrhosis: prevalence, impact, and management challenges.

Authors:  Marie Bruyneel; Thomas Sersté
Journal:  Nat Sci Sleep       Date:  2018-11-02

Review 4.  Comprehensive Overview of Sleep Disorders in Patients with Chronic Liver Disease.

Authors:  Oana-Mihaela Plotogea; Madalina Ilie; Simona Bungau; Alexandru Laurentiu Chiotoroiu; Ana Maria Alexandra Stanescu; Camelia Cristina Diaconu
Journal:  Brain Sci       Date:  2021-01-22

5.  MELD Score Reflects the Mood, Sleep, and Daily Living Ability in Liver Transplantation Candidates: A Descriptive Study.

Authors:  Kaiji Ni; Chenglin Li; Yongbing Qian; Xia Sun; Yan Zhan; Ting Zeng; Siqi Zhu; Qiang Xia; Wei Feng; Yanli Luo
Journal:  Ann Transplant       Date:  2020-12-01       Impact factor: 1.530

Review 6.  Assessment and Management of Sleep Disturbance in Cirrhosis.

Authors:  Chiara Formentin; Maria Garrido; Sara Montagnese
Journal:  Curr Hepatol Rep       Date:  2018-02-13

7.  Symptom prevalence and quality of life of patients with end-stage liver disease: A systematic review and meta-analysis.

Authors:  Jen-Kuei Peng; Nilay Hepgul; Irene J Higginson; Wei Gao
Journal:  Palliat Med       Date:  2018-10-22       Impact factor: 4.762

  7 in total

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