Literature DB >> 24511208

A planar PDMS micropump using in-contact minimized-leakage check valves.

Junhui Ni1, Fengliang Huang2, Bin Wang3, Beizhi Li4, Qiao Lin3.   

Abstract

We present a micropump with a simple planar design featuring compliant in-contact check valves in a single layer, which allows for a simple structure and easy system integration. The micropump, based on poly(dimethylsiloxane) (PDMS), primarily consists of a pneumatically driven thin membrane, a pump chamber, and two in-plane check valves. The pair of check valves is based on an in-contact flap-stopper configuration and is able to minimize leakage flow, greatly enhancing the reliability and performance of the micropump. Systematic experimental characterization of the micropump has been performed in terms of the frequency response of the pumping flow rate with respect to factors including device geometry (e.g. chamber height) and operating parameters (e.g. pneumatic driving pressure and backpressure). The results demonstrate that this micropump is capable of reliably generating a maximum flow rate of 41 μL min-1 and operating against a high backpressure of up to 25 kPa. In addition, a lumped-parameter theoretical model for the planar micropump is also developed for accurate analysis of the device behavior. These results demonstrate the capability of this micropump for diverse applications in lab-on-a-chip systems.

Entities:  

Year:  2010        PMID: 24511208      PMCID: PMC3915938          DOI: 10.1088/0960-1317/20/9/095033

Source DB:  PubMed          Journal:  J Micromech Microeng        ISSN: 0960-1317            Impact factor:   1.881


  5 in total

Review 1.  Lab-on-a-chip systems for biomedical and environmental monitoring.

Authors:  J G E Gardeniers; A van den Berg
Journal:  Anal Bioanal Chem       Date:  2004-01-31       Impact factor: 4.142

2.  Surface micromachined electrostatically actuated micro peristaltic pump.

Authors:  Jun Xie; Jason Shih; Qiao Lin; Bozhi Yang; Yu-Chong Tai
Journal:  Lab Chip       Date:  2004-09-14       Impact factor: 6.799

Review 3.  The origins and the future of microfluidics.

Authors:  George M Whitesides
Journal:  Nature       Date:  2006-07-27       Impact factor: 49.962

4.  Photopolymerized check valve and its integration into a pneumatic pumping system for biocompatible sample delivery.

Authors:  JeongYun Kim; JuYeoul Baek; KiHwa Lee; YongDoo Park; Kyung Sun; TaeSoo Lee; SangHoon Lee
Journal:  Lab Chip       Date:  2006-06-15       Impact factor: 6.799

5.  Rapid Prototyping of Microfluidic Systems in Poly(dimethylsiloxane).

Authors:  D C Duffy; J C McDonald; O J Schueller; G M Whitesides
Journal:  Anal Chem       Date:  1998-12-01       Impact factor: 6.986

  5 in total
  4 in total

1.  A Microfluidic Approach to Pulsatile Delivery of Drugs for Neurobiological Studies.

Authors:  Bin Wang; Junhui Ni; Yoav Litvin; Donald W Pfaff; Qiao Lin
Journal:  J Microelectromech Syst       Date:  2012-02       Impact factor: 2.417

Review 2.  A Review of Capillary Pressure Control Valves in Microfluidics.

Authors:  Shaoxi Wang; Xiafeng Zhang; Cong Ma; Sheng Yan; David Inglis; Shilun Feng
Journal:  Biosensors (Basel)       Date:  2021-10-19

3.  Electromagnetically-actuated reciprocating pump for high-flow-rate microfluidic applications.

Authors:  Ming-Tsun Ke; Jian-Hao Zhong; Chia-Yen Lee
Journal:  Sensors (Basel)       Date:  2012-09-26       Impact factor: 3.576

4.  Integrated Microfluidic Isolation of Aptamers Using Electrophoretic Oligonucleotide Manipulation.

Authors:  Jinho Kim; Timothy R Olsen; Jing Zhu; John P Hilton; Kyung-Ae Yang; Renjun Pei; Milan N Stojanovic; Qiao Lin
Journal:  Sci Rep       Date:  2016-05-24       Impact factor: 4.379

  4 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.