Literature DB >> 24510828

Gene electrotransfer in clinical trials.

Julie Gehl1.   

Abstract

Electroporation is increasingly being used for delivery of chemotherapy to tumors. Likewise, gene delivery by electroporation is rapidly gaining momentum for both vaccination purposes and for delivery of genes coding for other therapeutic molecules, such as chronic diseases or cancer. This chapter describes how gene therapy may be performed using electric pulses to enhance uptake and expression.

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Year:  2014        PMID： 24510828     DOI： 10.1007/978-1-4614-9632-8_21

Source DB:  PubMed          Journal:  Methods Mol Biol        ISSN： 1064-3745


  2 in total

1.  The Effect of Millisecond Pulsed Electric Fields (msPEF) on Intracellular Drug Transport with Negatively Charged Large Nanocarriers Made of Solid Lipid Nanoparticles (SLN): In Vitro Study.

Authors:  Julita Kulbacka; Agata Pucek; Kazimiera Anna Wilk; Magda Dubińska-Magiera; Joanna Rossowska; Marek Kulbacki; Małgorzata Kotulska
Journal:  J Membr Biol       Date:  2016-05-12       Impact factor: 1.843

2.  Evaluation of a Novel Plasmid for Simultaneous Gene Electrotransfer-Mediated Silencing of CD105 and CD146 in Combination with Irradiation.

Authors:  Monika Savarin; Urska Kamensek; Katarina Znidar; Vesna Todorovic; Gregor Sersa; Maja Cemazar
Journal:  Int J Mol Sci       Date:  2021-03-17       Impact factor: 5.923
  2 in total

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