Literature DB >> 24510291

DNA immunization.

Shixia Wang1, Shan Lu1.   

Abstract

DNA immunization was discovered in early 1990s, and its use has been expanded from vaccine studies to a broader range of biomedical research areas, such as the generation of high-quality polyclonal and monoclonal antibodies as research reagents. In this unit, three common DNA immunization methods are described: needle injection, electroporation, and gene gun. In addition, several common considerations related to DNA immunization are discussed.
Copyright © 2013 John Wiley & Sons, Inc.

Entities:  

Keywords:  DNA vaccine; electroporation; gene gun; immunization

Mesh:

Substances:

Year:  2013        PMID: 24510291      PMCID: PMC3920301          DOI: 10.1002/9780471729259.mc1803s31

Source DB:  PubMed          Journal:  Curr Protoc Microbiol        ISSN: 1934-8525


  5 in total

1.  Vaccine focusing to cross-subtype HIV-1 gp120 variable loop epitopes.

Authors:  Timothy Cardozo; Shixia Wang; Xunqing Jiang; Xiang-Peng Kong; Catarina Hioe; Chavdar Krachmarov
Journal:  Vaccine       Date:  2014-07-18       Impact factor: 3.641

2.  Development and Validation of Rapid In-House Diagnostic ELISA Kits for Detection of Human Orthopneumovirus in Clinical Samples.

Authors:  Ibrahim M Aziz; Mohamed A Farrag; Rauf Bhat; Anwar Ahmed; Noorah A Alkubaisi; Rasha M Alzayed; Gani Asa Dudin; Fahad N Almajhdi
Journal:  Diagnostics (Basel)       Date:  2022-04-06

3.  The dynamics of immunoglobulin V-gene usage and clonotype expansion in mice after prime and boost immunizations as analyzed by NGS.

Authors:  Diego J Farfán-Arribas; Shuying Liu; Shixia Wang; Shan Lu
Journal:  Hum Vaccin Immunother       Date:  2017-10-19       Impact factor: 3.452

4.  Codon optimization and improved delivery/immunization regimen enhance the immune response against wild-type and drug-resistant HIV-1 reverse transcriptase, preserving its Th2-polarity.

Authors:  A A Latanova; S Petkov; A Kilpelainen; J Jansons; O E Latyshev; Y V Kuzmenko; J Hinkula; M A Abakumov; V T Valuev-Elliston; M Gomelsky; V L Karpov; F Chiodi; B Wahren; D Y Logunov; E S Starodubova; M G Isaguliants
Journal:  Sci Rep       Date:  2018-05-24       Impact factor: 4.379

5.  Safety and immunogenicity of two recombinant DNA COVID-19 vaccines containing the coding regions of the spike or spike and nucleocapsid proteins: an interim analysis of two open-label, non-randomised, phase 1 trials in healthy adults.

Authors:  Jin Young Ahn; Jeongsoo Lee; You Suk Suh; Young Goo Song; Yoon-Jeong Choi; Kyoung Hwa Lee; Sang Hwan Seo; Manki Song; Jong-Won Oh; Minwoo Kim; Han Yeong Seo; Jeong-Eun Kwak; Jin Won Youn; Jung Won Woo; Eui-Cheol Shin; Young Chul Sung; Su-Hyung Park; Jun Yong Choi
Journal:  Lancet Microbe       Date:  2022-02-08
  5 in total

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