Stephen O Amoo1, Adeyemi O Aremu1, Johannes Van Staden2. 1. Research Centre for Plant Growth and Development, School of Life Sciences, University of KwaZulu-Natal Pietermaritzburg, Private Bag X01, Scottsville 3209, South Africa. 2. Research Centre for Plant Growth and Development, School of Life Sciences, University of KwaZulu-Natal Pietermaritzburg, Private Bag X01, Scottsville 3209, South Africa. Electronic address: rcpgd@ukzn.ac.za.
Abstract
ETHNOPHARMACOLOGICAL RELEVANCE: Aloe species (family: Xanthorrhoeaceae) are widely used in ethnomedicine for treating various ailments. Approximately 125 Aloe taxa are documented as indigenous to South Africa. This review was aimed at critically evaluating the available data on the ethnomedicinal uses, pharmacological activities, safety and conservation status of the documented South African Aloe species. MATERIALS AND METHODS: A detailed search using major electronic search engines (such as Google Scholar, Scopus and Scirus) and ethnobotanical literature was undertaken. Search terms used included 'medicinal properties of Aloe species', 'biological activity of South African Aloe species' and 'safety and toxicological evaluation of aloes'. RESULTS: Although Aloe species are widely used as laxatives and for treating wound and skin-related ailments, only about 20% of South African Aloe species have been clearly documented for their medicinal uses. The pharmacological potential including the antimicrobial, antiinflammatory, antiplasmodial and anthelmintic activities of some of the species has been established, providing a rationale for their use in traditional medicine. Successful micropropagation protocols have been developed as a conservation strategy, but only for a few species. CONCLUSIONS: The highlighted medicinal activities of some Aloe species indicate their therapeutic potential. Nonetheless, further research especially on the understudied species is required to properly document their ethnomedicinal uses and fully explore their pharmacological value.
ETHNOPHARMACOLOGICAL RELEVANCE: Aloe species (family: Xanthorrhoeaceae) are widely used in ethnomedicine for treating various ailments. Approximately 125 Aloe taxa are documented as indigenous to South Africa. This review was aimed at critically evaluating the available data on the ethnomedicinal uses, pharmacological activities, safety and conservation status of the documented South African Aloe species. MATERIALS AND METHODS: A detailed search using major electronic search engines (such as Google Scholar, Scopus and Scirus) and ethnobotanical literature was undertaken. Search terms used included 'medicinal properties of Aloe species', 'biological activity of South African Aloe species' and 'safety and toxicological evaluation of aloes'. RESULTS: Although Aloe species are widely used as laxatives and for treating wound and skin-related ailments, only about 20% of South African Aloe species have been clearly documented for their medicinal uses. The pharmacological potential including the antimicrobial, antiinflammatory, antiplasmodial and anthelmintic activities of some of the species has been established, providing a rationale for their use in traditional medicine. Successful micropropagation protocols have been developed as a conservation strategy, but only for a few species. CONCLUSIONS: The highlighted medicinal activities of some Aloe species indicate their therapeutic potential. Nonetheless, further research especially on the understudied species is required to properly document their ethnomedicinal uses and fully explore their pharmacological value.
Authors: Abdulrahman Ali Alzandi; Essam Ahmed Taher; Mohamed Azizi; Nageeb A Al-Sagheer; Abdul Wali Al-Khulaidi; Deyala M Naguib Journal: J Gastrointest Cancer Date: 2022-01-05
Authors: Anis Ahamed; A Panneerselvam; Abdullah Alaklabi; Ibrahim A Arif; V Ambikapathy; N Thajuddin Journal: Saudi J Biol Sci Date: 2019-12-17 Impact factor: 4.219