| Literature DB >> 24508089 |
G Usha Rani1, Ananda Kumar Konreddy1, Sumit Mishra2, Gautam Sen1.
Abstract
Agar has been modified by microwave assisted grafting with acrylamide monomer, resulting in poly acrylamide grafted agar (Ag-g-PAM). The synthesized grades of Ag-g-PAM were characterized by standard physico-chemical characterization techniques (FTIR spectroscopy, elemental analysis, scanning electron microscopy (SEM)) to ascertain the intended grafting. The synthesized graft copolymer (Ag-g-PAM) has been investigated (in vitro) for controlled and colon targeted release of 5-amino salicylic acid (5-ASA).Entities:
Keywords: 5-Amino salicylic acid; Agar; Controlled drug release; Microwave assisted synthesis; Polyacrylamide grafted agar
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Year: 2014 PMID： 24508089 DOI： 10.1016/j.ijbiomac.2014.01.034
Source DB: PubMed Journal: Int J Biol Macromol ISSN： 0141-8130 Impact factor: 6.953