Kyoung Sub Lee1, Jong Rak Lee1, Michael S Kook2. 1. Department of Ophthalmology, College of Medicine, University of Ulsan, Asan Medical Center, Seoul, Korea. 2. Department of Ophthalmology, College of Medicine, University of Ulsan, Asan Medical Center, Seoul, Korea. Electronic address: mskook@amc.seoul.kr.
Abstract
PURPOSE: To investigate the ocular features of companion eyes in an attempt to find eye-related factors that are associated with unilateral glaucomatous-appearing visual field (VF) defects in young myopic subjects. DESIGN: Retrospective, cross-sectional study. PARTICIPANTS: Thirty-nine patients (age range, 20-50 years) with unilateral glaucomatous-appearing VF defect and myopia. METHODS: A comparison was performed between VF-affected eyes and contralateral normal eyes. Optic disc torsion and tilt ratio were measured from disc photographs. Logistic regression analysis and linear regression analysis were performed to investigate various ocular parameters, including torsion degree and tilt ratio, that may be associated with the presence and severity of VF defect. MAIN OUTCOME MEASURES: Torsion degree, tilt ratio, and the severity of VF defect. RESULTS: Optic disc torsion degree (16.63±9.78°) of VF-affected eyes was statistically greater than that of the normal contralateral eyes (8.69±7.28°; P<0.001). Optic disc torsion was more prevalent in VF-affected eyes (66.6%) than in normal contralateral eyes (15.3%; P<0.001). In the multivariate analysis, the degree of optic disc torsion was associated significantly with the presence of VF defect (P = 0.005). The torsion degree (P = 0.006) and retinal nerve fiber layer thickness (P = 0.004) were associated significantly with the severity of VF defect. CONCLUSIONS: The prevalence and degree of optic disc torsion in the VF-affected eyes were significantly greater than those of contralateral normal eyes in unilateral, young, myopic patients with glaucomatous-appearing VF defect. Optic disc torsion should be considered in the presence of unilateral glaucomatous-appearing VF defect in young myopic eyes.
PURPOSE: To investigate the ocular features of companion eyes in an attempt to find eye-related factors that are associated with unilateral glaucomatous-appearing visual field (VF) defects in young myopic subjects. DESIGN: Retrospective, cross-sectional study. PARTICIPANTS: Thirty-nine patients (age range, 20-50 years) with unilateral glaucomatous-appearing VF defect and myopia. METHODS: A comparison was performed between VF-affected eyes and contralateral normal eyes. Optic disc torsion and tilt ratio were measured from disc photographs. Logistic regression analysis and linear regression analysis were performed to investigate various ocular parameters, including torsion degree and tilt ratio, that may be associated with the presence and severity of VF defect. MAIN OUTCOME MEASURES: Torsion degree, tilt ratio, and the severity of VF defect. RESULTS: Optic disc torsion degree (16.63±9.78°) of VF-affected eyes was statistically greater than that of the normal contralateral eyes (8.69±7.28°; P<0.001). Optic disc torsion was more prevalent in VF-affected eyes (66.6%) than in normal contralateral eyes (15.3%; P<0.001). In the multivariate analysis, the degree of optic disc torsion was associated significantly with the presence of VF defect (P = 0.005). The torsion degree (P = 0.006) and retinal nerve fiber layer thickness (P = 0.004) were associated significantly with the severity of VF defect. CONCLUSIONS: The prevalence and degree of optic disc torsion in the VF-affected eyes were significantly greater than those of contralateral normal eyes in unilateral, young, myopic patients with glaucomatous-appearing VF defect. Optic disc torsion should be considered in the presence of unilateral glaucomatous-appearing VF defect in young myopic eyes.
Authors: Jong Rak Lee; Jiyun Lee; Jong-Eun Lee; Jin Young Lee; Michael S Kook Journal: Graefes Arch Clin Exp Ophthalmol Date: 2016-10-06 Impact factor: 3.117
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Authors: Eun Young Choi; Raymond C S Wong; Thuzar Thein; Louis R Pasquale; Lucy Q Shen; Mengyu Wang; Dian Li; Qingying Jin; Hui Wang; Neda Baniasadi; Michael V Boland; Siamak Yousefi; Sarah R Wellik; Carlos G De Moraes; Jonathan S Myers; Peter J Bex; Tobias Elze Journal: J Clin Med Date: 2021-06-25 Impact factor: 4.964