Literature DB >> 24506794

The discard of deceased donor kidneys in the UK.

Chris J Callaghan1, Simon J F Harper, Kourosh Saeb-Parsy, Alex Hudson, Paul Gibbs, Christopher J E Watson, Raaj K Praseedom, Andrew J Butler, Gavin J Pettigrew, J Andrew Bradley.   

Abstract

It is essential to minimize the unnecessary discard of procured deceased donor kidneys, but information on discard rates and the extent to which discard can be avoided are limited. Analysis of the UK Transplant Registry revealed that the discard rate of procured deceased donor kidneys has increased from 5% in 2002-3 to 12% in 2011-12. A national offering system for hard-to-place kidneys was introduced in the UK in 2006 (the Declined Kidney Scheme), but just 13% of kidneys that were subsequently discarded until 2012 were offered through the scheme. In order to examine the appropriateness of discard, 20 consecutive discarded kidneys from 13 deceased donors were assessed to determine if surgeons agreed with the decision that they were not implantable. Donors had a median (range) age of 67 (31-80) yr. Kidneys had been offered to a median of 3 (1-12) centers before discard. Four (20%) of the discarded kidneys were thought to be usable, and nine (45%) were possibly usable. As a result of these findings, major changes to the UK deceased donor kidney offering system have been implemented, including simultaneous offering and broader entry criteria for hard-to-place kidneys. Organizational changes are necessary to improve utilization of deceased donor kidneys.
© 2014 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

Entities:  

Keywords:  allocation; deceased donor kidneys; discarded organs; expanded criteria donors; organ utilization

Mesh:

Year:  2014        PMID: 24506794     DOI: 10.1111/ctr.12319

Source DB:  PubMed          Journal:  Clin Transplant        ISSN: 0902-0063            Impact factor:   2.863


  20 in total

1.  Factors leading to the discard of deceased donor kidneys in the United States.

Authors:  Sumit Mohan; Mariana C Chiles; Rachel E Patzer; Stephen O Pastan; S Ali Husain; Dustin J Carpenter; Geoffrey K Dube; R John Crew; Lloyd E Ratner; David J Cohen
Journal:  Kidney Int       Date:  2018-05-05       Impact factor: 10.612

Review 2.  Kidney donation after circulatory death (DCD): state of the art.

Authors:  Dominic M Summers; Christopher J E Watson; Gavin J Pettigrew; Rachel J Johnson; David Collett; James M Neuberger; J Andrew Bradley
Journal:  Kidney Int       Date:  2015-03-18       Impact factor: 10.612

3.  Comparison of normothermic and hypothermic perfusion in porcine kidneys donated after cardiac death.

Authors:  Matthew F Blum; Qiang Liu; Basem Soliman; Paul Dreher; Toshihiro Okamoto; Emilio D Poggio; David A Goldfarb; William M Baldwin; Cristiano Quintini
Journal:  J Surg Res       Date:  2017-04-20       Impact factor: 2.192

4.  Declined Offers for Deceased Donor Kidneys Are Not an Independent Reflection of Organ Quality.

Authors:  Kristen L King; Sulemon G Chaudhry; Lloyd E Ratner; David J Cohen; S Ali Husain; Sumit Mohan
Journal:  Kidney360       Date:  2021-08-24

5.  Magnetic resonance imaging assessment of renal flow distribution patterns during ex vivo normothermic machine perfusion in porcine and human kidneys.

Authors:  Rianne Schutter; Veerle A Lantinga; Tim L Hamelink; Merel B F Pool; Otis C van Varsseveld; Jan Hendrik Potze; Jan-Luuk Hillebrands; Marius C van den Heuvel; Rudi A J O Dierckx; Henri G D Leuvenink; Cyril Moers; Ronald J H Borra
Journal:  Transpl Int       Date:  2021-09       Impact factor: 3.842

6.  Characteristics and Performance of Unilateral Kidney Transplants from Deceased Donors.

Authors:  Syed Ali Husain; Mariana C Chiles; Samnang Lee; Stephen O Pastan; Rachel E Patzer; Bekir Tanriover; Lloyd E Ratner; Sumit Mohan
Journal:  Clin J Am Soc Nephrol       Date:  2017-12-07       Impact factor: 8.237

7.  The weekend effect alters the procurement and discard rates of deceased donor kidneys in the United States.

Authors:  Sumit Mohan; Karl Foley; Mariana C Chiles; Geoffrey K Dube; Rachel E Patzer; Stephen O Pastan; R John Crew; David J Cohen; Lloyd E Ratner
Journal:  Kidney Int       Date:  2016-05-12       Impact factor: 10.612

8.  Prospective Validation of Prediction Model for Kidney Discard.

Authors:  Sheng Zhou; Allan B Massie; Courtenay M Holscher; Madeleine M Waldram; Tanveen Ishaque; Alvin G Thomas; Dorry L Segev
Journal:  Transplantation       Date:  2019-04       Impact factor: 4.939

9.  Epidemiology of Kidney Discard from Expanded Criteria Donors Undergoing Donation after Circulatory Death.

Authors:  Sunita K Singh; S Joseph Kim
Journal:  Clin J Am Soc Nephrol       Date:  2015-12-14       Impact factor: 8.237

10.  Predicting Kidney Discard Using Machine Learning.

Authors:  Masoud Barah; Sanjay Mehrotra
Journal:  Transplantation       Date:  2021-09-01       Impact factor: 5.385

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