Literature DB >> 24506313

Melanocytoma of the Optic Nerve Head, Thirty-Month Follow-Up.

Hasan Eldaly1, Zeiad Eldaly2.   

Abstract

INTRODUCTION: Optic nerve head (ONH) melanocytoma is a benign pigmented tumor that is detected as a dark brown mass on or adjacent to the optic disc. Ultrasonography, optical coherence tomography (OCT), and fundus fluorescein angiography (FFA) can be used to differentiate it from other pigmented tumor as well as to monitor tumor growth. Visual field changes are variable in ONH melanocytoma. Usually, ONH melanocytoma has a stationary course with few cases of progressive growth or malignant transformation. CASE
PRESENTATION: A 54-year-old female complained of blurring of vision. Best-corrected visual acuity (BCVA) was 0.9 in both eyes. On routine fundus examination, an elevated pigmented lesion was found, involving the optic nerve head of the left eye. B-scan ultrasound demonstrated a mass arising from ONH. FFA revealed blocked fluorescence corresponding to pigmented mass. HR-OCT scans showed a dome-shaped, elevated ONH lesion with highly reflective layer and optical shadowing behind it, obscuring most of the optic nerve head details. On regular follow-up for 30 months, the lesion had neither changed in its size nor affected the patient's visual acuity.
CONCLUSION: ONH melanocytoma is a benign tumor with rare malignant transformation and visual impairment.

Entities:  

Keywords:  Blocked fluorescence; blurring of vision; malignant transformation; optical coherence tomography; pigmented optic nerve head lesion

Mesh:

Year:  2014        PMID: 24506313     DOI: 10.3109/08820538.2013.874485

Source DB:  PubMed          Journal:  Semin Ophthalmol        ISSN: 0882-0538            Impact factor:   1.975


  4 in total

1.  Clinical and Spectral-Domain Optical Coherence Tomography Appearance of Optic Disc Melanocytoma: A New Classification and Differentiation from Pigmented Choroidal Lesions.

Authors:  Supanut Apinyawasisuk; Tara McCannel; Anthony C Arnold
Journal:  Ocul Oncol Pathol       Date:  2016-12-14

2.  Optical coherence tomography angiography characteristics of choroidal melanoma.

Authors:  Nan Zhou; Xiaolin Xu; Wenbin Wei
Journal:  Eye (Lond)       Date:  2020-11-09       Impact factor: 4.456

3.  Clinical findings and genetic expression profiling of three pigmented lesions of the optic nerve.

Authors:  Manuel A de Alba; Victor M Villegas; Aaron S Gold; Andrea Wildner; Fiona J Ehlies; Azeema Latiff; Timothy G Murray
Journal:  Case Rep Ophthalmol Med       Date:  2015-04-23

4.  Optical coherence tomography angiography characteristics of optic disc melanocytoma.

Authors:  Nan Zhou; Xiaolin Xu; Wenbin Wei
Journal:  BMC Ophthalmol       Date:  2020-10-27       Impact factor: 2.209

  4 in total

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