Literature DB >> 24503664

Polyarteritis nodosa presenting as profuse gastrointestinal bleeding.

Gaurang Nandkishor Vaidya1, Arman Khorasani-Zadeh, Savio John.   

Abstract

A 70-year-old man presented with acute onset of profuse bleeding per rectum. An urgent colonoscopy showed blood throughout the colon and distal ileum but failed to localise the source. Subsequent visceral arteriography revealed pseudoaneurysms of the branches of the superior mesenteric artery and left gastric artery. The bleeding stopped spontaneously and the aetiology of the bleeding was later found out to be secondary to polyarteritis nodosa (PAN). The presence of profuse gastrointestinal bleeding as the sole manifestation at presentation in PAN is under-reported. Early diagnosis of PAN in patients with haemodynamically significant bleeding is necessary as prompt initiation of immunosuppressive therapy helps prevent relapses. With this case report, we highlight one of the unusual presentations of PAN and the favourable response to immunosuppression with pulsed dose steroids.

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Mesh:

Year:  2014        PMID: 24503664      PMCID: PMC3918604          DOI: 10.1136/bcr-2013-202925

Source DB:  PubMed          Journal:  BMJ Case Rep        ISSN: 1757-790X


  14 in total

1.  Gastrointestinal involvement in polyarteritis nodosa (1986-2000): presentation and outcomes in 24 patients.

Authors:  Stuart M Levine; David B Hellmann; John H Stone
Journal:  Am J Med       Date:  2002-04-01       Impact factor: 4.965

2.  Microscopic polyangiitis and polyarteritis nodosa: how and when do they start?

Authors:  Christian Agard; Luc Mouthon; Alfred Mahr; Loïc Guillevin
Journal:  Arthritis Rheum       Date:  2003-10-15

3.  Fatal polyarteritis nodosa with gastrointestinal involvement in a child.

Authors:  Tanl Kendirli; Selçuk Yüksel; Mehmet Oral; Necmettin Unal; Melek Tulunay; Umman Sanl Dilek; Fatoş Yalçnkaya
Journal:  Pediatr Emerg Care       Date:  2006-12       Impact factor: 1.454

4.  Clinical features and outcomes in 348 patients with polyarteritis nodosa: a systematic retrospective study of patients diagnosed between 1963 and 2005 and entered into the French Vasculitis Study Group Database.

Authors:  Christian Pagnoux; Raphaèle Seror; Corneliu Henegar; Alfred Mahr; Pascal Cohen; Véronique Le Guern; Boris Bienvenu; Luc Mouthon; Loïc Guillevin
Journal:  Arthritis Rheum       Date:  2010-02

5.  New features of disease after diagnosis in 6 forms of systemic vasculitis.

Authors:  Peter C Grayson; David Cuthbertson; Simon Carette; Gary S Hoffman; Nader A Khalidi; Curry L Koening; Carol A Langford; Kathleen Maksimowicz-McKinnon; Paul A Monach; Philip Seo; Ulrich Specks; Steven R Ytterberg; Peter A Merkel
Journal:  J Rheumatol       Date:  2013-08-01       Impact factor: 4.666

6.  Polyarteritis nodosa presenting as massive upper gastrointestinal hemorrhage.

Authors:  R A Perez; D Silver; B Banerjee
Journal:  Surg Endosc       Date:  1999-10-22       Impact factor: 4.584

7.  Arterial interventions in gastrointestinal bleeding.

Authors:  Mathew P Cherian; Pankaj Mehta; Tejas M Kalyanpur; Sandeep S Hedgire; Kaustubh S Narsinghpura
Journal:  Semin Intervent Radiol       Date:  2009-09       Impact factor: 1.513

Review 8.  Gastrointestinal involvement in polyarteritis nodosa.

Authors:  Ellen C Ebert; Klaus D Hagspiel; Michael Nagar; Naomi Schlesinger
Journal:  Clin Gastroenterol Hepatol       Date:  2008-06-27       Impact factor: 11.382

9.  Polyarteritis nodosa, presenting as life-threatening gastrointestinal hemorrhage in a liver transplant recipient.

Authors:  Sheldon C Cooper; Simon P Olliff; Ian McCafferty; Stephen J Wigmore; Darius F Mirza
Journal:  Liver Transpl       Date:  2008-02       Impact factor: 5.799

10.  Computed tomography angiography in the diagnosis of ANCA-associated small- and medium-vessel vasculitis.

Authors:  Neeraj Dhaun; Dilip Patel; David C Kluth
Journal:  Am J Kidney Dis       Date:  2013-04-10       Impact factor: 8.860

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