| Literature DB >> 24503599 |
Zhi-lun Zhang1, Xiang-jun Zhu1, Ai-lan Shan1, Zhi-gang Gao1, Ying Zhang1, Ya-xing Ding1, Hui Liu1, Wei-shen Wu1, Yong Liu1, Hai-yan He1, Xiao-hua Xie1, Wei-dong Xia1, Chao Li1, Wen-ti Xu1, Zhi-yuan Li2, Hua-liang Lin3, Wei-ming Fu4.
Abstract
Vaccination is an effective strategy to prevent and control the transmission of hepatitis A. Hepatitis A immunization program has been taken into effect since 2001 in Tianjin, China. This study evaluated the effectiveness of strategies in the prevention and control of hepatitis A. Data of serological survey, annual hepatitis A incidence, immunization coverage and the positive rate of hepatitis A IgG before and after the immunization program in residents under 15 years old were used to do the analysis. The results indicated that hepatitis A vaccine induced a striking decrease of hepatitis A incidence and a significant increase in the positive rate of anti-HAV IgG among the children younger than 15 years old. Hepatitis A vaccination in children was proved to be effective in the prevention and control of hepatitis A in Tianjin, China.Entities:
Keywords: Tianjin; epidemic; hepatitis A; hepatitis A vaccination; immunization
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Year: 2014 PMID： 24503599 PMCID： PMC4896570 DOI： 10.4161/hv.27775
Source DB: PubMed Journal: Hum Vaccin Immunother ISSN： 2164-5515 Impact factor: 3.452