Literature DB >> 24501389

Low concentrations of HIV-1 DNA at birth delays diagnosis, complicating identification of infants for antiretroviral therapy to potentially prevent the establishment of viral reservoirs.

Caroline Mitchell1, Sandra Dross, Ingrid A Beck, Mark A Micek, Lisa M Frenkel.   

Abstract

Among infants exposed to human immunodeficiency virus type 1 (HIV-1), detection of viral infection at birth was increased by 39% (95% confidence interval, 19%-47%) by increasing DNA input from dried blood spots into polymerase chain reaction. Infants with low concentrations of HIV-1 at birth may be the best target population to evaluate whether immediate antiretroviral therapy can prevent long-term infection.

Entities:  

Keywords:  HIV-1; HIV-1 DNA; HIV-1 cure; infant diagnosis; mother-to-child transmission

Mesh：

Substances：

Year:  2014        PMID： 24501389      PMCID： PMC3967830          DOI： 10.1093/cid/ciu068

Source DB:  PubMed          Journal:  Clin Infect Dis        ISSN： 1058-4838            Impact factor:   9.079


  13 in total

1.  Understanding the timing of HIV transmission from mother to infant.

Authors:  A P Kourtis; M Bulterys; S R Nesheim; F K Lee
Journal:  JAMA       Date:  2001-02-14       Impact factor: 56.272

2.  Early detection of perinatal human immunodeficiency virus (HIV) type 1 infection using HIV RNA amplification and detection. New York City Perinatal HIV Transmission Collaborative Study.

Authors:  R W Steketee; E J Abrams; D M Thea; T M Brown; G Lambert; S Orloff; J Weedon; M Bamji; E E Schoenbaum; J Rapier; M L Kalish
Journal:  J Infect Dis       Date:  1997-03       Impact factor: 5.226

3.  Nevirapine resistance by timing of HIV type 1 infection in infants treated with single-dose nevirapine.

Authors:  Mark A Micek; Ana Judith Blanco; Ingrid A Beck; Sandra Dross; Laurinda Matunha; Pablo Montoya; Kristy Seidel; Soren Gantt; Eduardo Matediane; Lilia Jamisse; Stephen Gloyd; Lisa M Frenkel
Journal:  Clin Infect Dis       Date:  2010-05-15       Impact factor: 9.079

4.  Coamplification of HIV type 1 and beta-globin gene DNA sequences in a nonisotopic polymerase chain reaction assay to control for amplification efficiency.

Authors:  F Coutlée; Y He; P Saint-Antoine; C Olivier; A Kessous
Journal:  AIDS Res Hum Retroviruses       Date:  1995-03       Impact factor: 2.205

5.  Simple, sensitive, and specific detection of human immunodeficiency virus type 1 subtype B DNA in dried blood samples for diagnosis in infants in the field.

Authors:  I A Beck; K D Drennan; A J Melvin; K M Mohan; A M Herz; J Alarcón; J Piscoya; C Velázquez; L M Frenkel
Journal:  J Clin Microbiol       Date:  2001-01       Impact factor: 5.948

6.  Absence of detectable HIV-1 viremia after treatment cessation in an infant.

Authors:  Deborah Persaud; Hannah Gay; Carrie Ziemniak; Ya Hui Chen; Michael Piatak; Tae-Wook Chun; Matthew Strain; Douglas Richman; Katherine Luzuriaga
Journal:  N Engl J Med       Date:  2013-10-23       Impact factor: 91.245

7.  Early diagnosis of in utero and intrapartum HIV infection in infants prior to 6 weeks of age.

Authors:  Rivka R Lilian; Emma Kalk; Kapila Bhowan; Leigh Berrie; Sergio Carmona; Karl Technau; Gayle G Sherman
Journal:  J Clin Microbiol       Date:  2012-04-18       Impact factor: 5.948

8.  Quantitative RNA testing for diagnosis of HIV-infected infants.

Authors:  Steven Nesheim; Paul Palumbo; Kevin Sullivan; Francis Lee; Peter Vink; Elaine Abrams; Marc Bulterys
Journal:  J Acquir Immune Defic Syndr       Date:  2003-02-01       Impact factor: 3.731

9.  Detection of low levels of human immunodeficiency virus (HIV) may be critical for early diagnosis of pediatric HIV infection by use of dried blood spots.

Authors:  Jan Walter; Louise Kuhn; Katherine Semrau; Don W Decker; Moses Sinkala; Chipepo Kankasa; Donald M Thea; Marc Bulterys; Chin-Yih Ou; Grace M Aldrovandi
Journal:  J Clin Microbiol       Date:  2009-07-22       Impact factor: 5.948

Review 10.  The polymerase chain reaction: a new tool for the understanding and diagnosis of HIV-1 infection at the molecular level.

Authors:  F Coutlée; R P Viscidi; P Saint-Antoine; A Kessous; R H Yolken
Journal:  Mol Cell Probes       Date:  1991-08       Impact factor: 2.365
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  9 in total

1.  Delayed HIV detection among infants exposed to postnatal antiretroviral prophylaxis during breastfeeding.

Authors:  Caroline C King; Athena P Kourtis; Deborah Persaud; Julie A E Nelson; Carrie Ziemniak; Michael G Hudgens; Gerald Tegha; Charles S Chasela; Denise J Jamieson; Charles M van der Horst
Journal:  AIDS       Date:  2015-09-24       Impact factor: 4.177

Review 2.  Total HIV-1 DNA, a Marker of Viral Reservoir Dynamics with Clinical Implications.

Authors:  Véronique Avettand-Fènoël; Laurent Hocqueloux; Jade Ghosn; Antoine Cheret; Pierre Frange; Adeline Melard; Jean-Paul Viard; Christine Rouzioux
Journal:  Clin Microbiol Rev       Date:  2016-10       Impact factor: 26.132

Review 3.  Very early combination antiretroviral therapy in infants: prospects for cure.

Authors:  Kaitlin Rainwater-Lovett; Katherine Luzuriaga; Deborah Persaud
Journal:  Curr Opin HIV AIDS       Date:  2015-01       Impact factor: 4.283

4.  HIV diagnostic challenges in breast-fed infants of mothers on antiretroviral therapy.

Authors:  Renate Strehlau; Maria Paximadis; Faeezah Patel; Megan Burke; Karl-Gunter Technau; Stephanie Shiau; Elaine J Abrams; Gayle G Sherman; Gillian Hunt; Johanna Ledwaba; Ahmad H Mazanderani; Caroline T Tiemessen; Louise Kuhn
Journal:  AIDS       Date:  2019-09-01       Impact factor: 4.177

5.  Negative Diagnostic PCR Tests in School-Aged, HIV-Infected Children on Antiretroviral Therapy Since Early Life in Johannesburg, South Africa.

Authors:  Faeezah Patel; Cara Thurman; Afaaf Liberty; Megan Burke; Renate Strehlau; Stephanie Shiau; Ashraf Coovadia; Elaine J Abrams; Avy Violari; Louise Kuhn
Journal:  J Acquir Immune Defic Syndr       Date:  2020-04-01       Impact factor: 3.771

6.  Dried blood spot specimen quality and validation of a new pre-analytical processing method for qualitative HIV-1 PCR, KwaZulu-Natal, South Africa.

Authors:  Kerusha Govender; Raveen Parboosing; Ntombizandile Siyaca; Pravikrishnen Moodley
Journal:  Afr J Lab Med       Date:  2016-02-25

7.  HIV testing during the neonatal period.

Authors:  Gayle G Sherman
Journal:  South Afr J HIV Med       Date:  2015-04-24       Impact factor: 2.744

8.  Research gaps in neonatal HIV-related care.

Authors:  Mary-Ann Davies
Journal:  South Afr J HIV Med       Date:  2015-05-20       Impact factor: 2.744

9.  Time to first positive HIV-1 DNA PCR may differ with antiretroviral regimen in infants infected with non-B subtype HIV-1.

Authors:  Raji Balasubramanian; Mary Glenn Fowler; Kenneth Dominguez; Shahin Lockman; Pat A Tookey; Nicole Ngo Giang Huong; Steven Nesheim; Michael D Hughes; Marc Lallemant; Jennifer Tosswill; Nathan Shaffer; Gayle Sherman; Paul Palumbo; David E Shapiro
Journal:  AIDS       Date:  2017-11-28       Impact factor: 4.177
  9 in total

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