Hugh D Tildesley1, Anthony M Wright2, Jeremy H M Chan3, Adel B Mazanderani4, Stuart A Ross5, Hamish G Tildesley6, Augustine M Lee7, Tricia S Tang7, Adam S White8. 1. Department of Endocrinology and Metabolism, St. Paul's Hospital, Vancouver, British Columbia, Canada; University of British Columbia, Vancouver, British Columbia, Canada. Electronic address: hdtildesley@gmail.com. 2. University of Victoria, Victoria, British Columbia, Canada. 3. Vanderbilt University, School of Medicine, Nashville, Tennessee, USA. 4. Saint George's University, Grenada, West Indies. 5. University of Calgary, Calgary, Alberta, Canada. 6. Dartmouth College, Hanover, New Hampshire, USA. 7. University of British Columbia, Vancouver, British Columbia, Canada. 8. Department of Endocrinology and Metabolism, St. Paul's Hospital, Vancouver, British Columbia, Canada; University of British Columbia, Vancouver, British Columbia, Canada.
Abstract
OBJECTIVE: To compare the effects of real-time continuous glucose monitoring (RT-CGM) and an Internet blood glucose monitoring system (IBGMS) on glycated hemoglobin levels in patients with type 2 diabetes mellitus treated with insulin. METHODS:Fifty-seven patients with type 2 diabetes treated with insulin were assigned randomly to 1 of 2 groups. Group 1 had the results of their self-monitoring of blood glucose level monitored biweekly using an IBGMS. Group 2 used RT-CGM and were monitored biweekly. Both groups used a secure website to upload data and to receive feedback from their endocrinologist. A1C and laboratory test results were collected at 0, 3 and 6 months. RESULTS: The baseline parameters were not significantly different. After a 6-month follow-up period, both IBGMS and RT-CGM showed significant within-group improvements in A1C level. In the IBGMS group, the A1C level decreased from 8.79%±1.25% to 7.96%±1.30% (p<0.05). The RT-CGM group decreased from 8.80%±1.37% to 7.49%±0.70% (p<0.001). IBGMS and RT-CGM did not show significantly different A1C levels at baseline, 3 and 6 months (p>0.05). CONCLUSIONS: The use of both IBGMS and RT-CGM significantly improved A1C levels in patients with type 2 diabetes treated withinsulin in a randomized trial over a 6-month period. There were no significant differences in A1C values between groups after 6 months.
RCT Entities:
OBJECTIVE: To compare the effects of real-time continuous glucose monitoring (RT-CGM) and an Internet blood glucose monitoring system (IBGMS) on glycated hemoglobin levels in patients with type 2 diabetes mellitus treated with insulin. METHODS: Fifty-seven patients with type 2 diabetes treated with insulin were assigned randomly to 1 of 2 groups. Group 1 had the results of their self-monitoring of blood glucose level monitored biweekly using an IBGMS. Group 2 used RT-CGM and were monitored biweekly. Both groups used a secure website to upload data and to receive feedback from their endocrinologist. A1C and laboratory test results were collected at 0, 3 and 6 months. RESULTS: The baseline parameters were not significantly different. After a 6-month follow-up period, both IBGMS and RT-CGM showed significant within-group improvements in A1C level. In the IBGMS group, the A1C level decreased from 8.79%±1.25% to 7.96%±1.30% (p<0.05). The RT-CGM group decreased from 8.80%±1.37% to 7.49%±0.70% (p<0.001). IBGMS and RT-CGM did not show significantly different A1C levels at baseline, 3 and 6 months (p>0.05). CONCLUSIONS: The use of both IBGMS and RT-CGM significantly improved A1C levels in patients with type 2 diabetes treated with insulin in a randomized trial over a 6-month period. There were no significant differences in A1C values between groups after 6 months.
Keywords:
Internet-based glucose monitoring; diabète de type 2; real-time continuous glucose monitoring; remote monitoring; surveillance du glucose en continu en temps réel; surveillance du glucose par Internet; surveillance à distance; type 2 diabetes
Authors: Nelson Chow; Daniel Shearer; Jessica Aydin Plaa; Betty Pottinger; Monika Pawlowska; Adam White; Hugh D Tildesley Journal: BMJ Open Diabetes Res Care Date: 2016-04-29