Literature DB >> 24497565

Rare coincident NPM1 and RUNX1 mutations in intermediate risk acute myeloid leukemia display similar patterns to single mutated cases.

Annette Fasan1, Claudia Haferlach, Alexander Kohlmann, Frank Dicker, Christiane Eder, Wolfgang Kern, Torsten Haferlach, Susanne Schnittger.   

Abstract

Entities:  

Keywords:  NPM1; RUNX1; acute myeloid leukemia; coincident mutations; intermediate risk

Mesh：

Substances：

Year:  2014        PMID： 24497565      PMCID： PMC3912979          DOI： 10.3324/haematol.2013.099754

Source DB:  PubMed          Journal:  Haematologica        ISSN： 0390-6078            Impact factor:   9.941


× No keyword cloud information.
  3 in total

1.  In rare acute myeloid leukemia patients harboring both RUNX1 and NPM1 mutations, RUNX1 mutations are unusual in structure and present in the germline.

Authors:  Jason H Mendler; Kati Maharry; Heiko Becker; Ann-Kathrin Eisfeld; Leigha Senter; Krzysztof Mrózek; Jessica Kohlschmidt; Klaus H Metzeler; Sebastian Schwind; Susan P Whitman; Jihane Khalife; Michael A Caligiuri; Rebecca B Klisovic; Joseph O Moore; Thomas H Carter; Guido Marcucci; Clara D Bloomfield
Journal:  Haematologica       Date:  2013-06-10       Impact factor: 9.941

2.  RUNX1 mutations are frequent in de novo AML with noncomplex karyotype and confer an unfavorable prognosis.

Authors:  Susanne Schnittger; Frank Dicker; Wolfgang Kern; Nicole Wendland; Jana Sundermann; Tamara Alpermann; Claudia Haferlach; Torsten Haferlach
Journal:  Blood       Date:  2010-12-09       Impact factor: 22.113

3.  AML with mutated NPM1 carrying a normal or aberrant karyotype show overlapping biologic, pathologic, immunophenotypic, and prognostic features.

Authors:  Claudia Haferlach; Cristina Mecucci; Susanne Schnittger; Alexander Kohlmann; Marco Mancini; Antonio Cuneo; Nicoletta Testoni; Giovanna Rege-Cambrin; Antonella Santucci; Marco Vignetti; Paola Fazi; Maria Paola Martelli; Torsten Haferlach; Brunangelo Falini
Journal:  Blood       Date:  2009-05-08       Impact factor: 22.113
  3 in total
  1 in total

1.  Reply to "rare coincident NPM1 and RUNX1 mutations in intermediate risk acute myeloid leukemia display similar patterns to single mutated cases". Haematologica 2014;99(2):e20-21.

Authors:  Jason H Mendler; Guido Marcucci; Clara D Bloomfield
Journal:  Haematologica       Date:  2014-02       Impact factor: 9.941
  1 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.