Literature DB >> 24496501

A tuned affinity-based staurosporine probe for in situ profiling of protein kinases.

Xiamin Cheng1, Lin Li, Mahesh Uttamchandani, Shao Q Yao.   

Abstract

A clickable and cell-permeable affinity-based probe (AfBP) was designed from staurosporine, by incorporating an electrophilic chloroacetamide warhead to facilitate in situ proteome labeling of a range of potential kinase targets.

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Year:  2014        PMID： 24496501     DOI： 10.1039/c4cc00184b

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  4 in total

1.  In situ Proteomic Profiling of Curcumin Targets in HCT116 Colon Cancer Cell Line.

Authors:  Jigang Wang; Jianbin Zhang; Chong-Jing Zhang; Yin Kwan Wong; Teck Kwang Lim; Zi-Chun Hua; Bin Liu; Steven R Tannenbaum; Han-Ming Shen; Qingsong Lin
Journal:  Sci Rep       Date:  2016-02-26       Impact factor: 4.379

2.  Quantitative Chemical Proteomics Reveals Resveratrol Inhibition of A549 Cell Migration Through Binding Multiple Targets to Regulate Cytoskeletal Remodeling and Suppress EMT.

Authors:  Xiao Chen; Yutong Wang; Jing Tian; Yurou Shao; Bo Zhu; Jigang Wang; Zichun Hua
Journal:  Front Pharmacol       Date:  2021-03-26       Impact factor: 5.810

Review 3.  Target identification of anticancer natural products using a chemical proteomics approach.

Authors:  Swadhapriya Bhukta; Pushparathinam Gopinath; Rambabu Dandela
Journal:  RSC Adv       Date:  2021-08-18       Impact factor: 4.036

4.  Alkylation of Staurosporine to Derive a Kinase Probe for Fluorescence Applications.

Authors:  Alexander J M Disney; Barrie Kellam; Lodewijk V Dekker
Journal:  ChemMedChem       Date:  2016-03-23       Impact factor: 3.466
  4 in total

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