Literature DB >> 24496296

An interdisciplinary approach to personalized medicine: case studies from a cardiogenetics clinic.

Kathleen E Erskine1, Eleanor Griffith2, Nicole Degroat3, Marina Stolerman4, Louise B Silverstein5, Nadia Hidayatallah5, David Wasserman6, Esma Paljevic7, Lilian Cohen8, Christine A Walsh9, Thomas McDonald10, Robert W Marion11, Siobhan M Dolan12.   

Abstract

In the genomic age, the challenges presented by various inherited conditions present a compelling argument for an interdisciplinary model of care. Cardiac arrhythmias with a genetic basis, such as long QT syndrome, require clinicians with expertise in many specialties to address the complex genetic, psychological, ethical and medical issues involved in treatment. The Montefiore-Einstein Center for CardioGenetics has been established to provide personalized, interdisciplinary care for families with a history of sudden cardiac death or an acute cardiac event. Four vignettes of patient care are presented to illustrate the unique capacity of an interdisciplinary model to address genetic, psychological, ethical and medical issues. Because interdisciplinary clinics facilitate collaboration among multiple specialties, they allow for individualized, comprehensive care to be delivered to families who experience complex inherited medical conditions. As the genetic basis of many complex conditions is discovered, the advantages of an interdisciplinary approach for delivering personalized medicine will become more evident.

Entities:  

Keywords:  cardiogenetics; interdisciplinary; long QT syndrome; multidisciplinary; personalized medicine

Year:  2013        PMID: 24496296      PMCID: PMC3564672          DOI: 10.2217/pme.12.108

Source DB:  PubMed          Journal:  Per Med        ISSN: 1741-0541            Impact factor:   2.512


  29 in total

Review 1.  Good care for people with cystic fibrosis.

Authors:  J M Littlewood
Journal:  Paediatr Respir Rev       Date:  2000-06       Impact factor: 2.726

Review 2.  Clinical practice. Long-QT syndrome.

Authors:  Dan M Roden
Journal:  N Engl J Med       Date:  2008-01-10       Impact factor: 91.245

Review 3.  Quality of life and psychological status of patients with implantable cardioverter defibrillators.

Authors:  Sue Ann Thomas; Erika Friedmann; Chi-Wen Kao; Pia Inguito; Matthew Metcalf; Frances J Kelley; Steven S Gottlieb
Journal:  Am J Crit Care       Date:  2006-07       Impact factor: 2.228

4.  The short- and long-term impact of multi-disciplinary clinics in addition to standard nephrology care on patient outcomes.

Authors:  Bryan M Curtis; Pietro Ravani; F Malberti; Fiona Kennett; Paul A Taylor; Ognjenka Djurdjev; Adeera Levin
Journal:  Nephrol Dial Transplant       Date:  2004-12-07       Impact factor: 5.992

5.  Improving access to breast health services with an interdisciplinary model of care.

Authors:  Mario R Castellanos; Joseph Conte; Dina Abi Fadel; Carolyn Raia; Frank Forte; Kathleen Ahern; Marianne Smith; Danny Elsayeh; Shalom Buchbinder
Journal:  Breast J       Date:  2008 Jul-Aug       Impact factor: 2.431

6.  Recurrence rates for sudden infant death syndrome (SIDS): the importance of risk stratification.

Authors:  M J Campbell; D Hall; T Stephenson; C Bacon; J Madan
Journal:  Arch Dis Child       Date:  2008-05-22       Impact factor: 3.791

Review 7.  Long QT syndrome.

Authors:  Ilan Goldenberg; Arthur J Moss
Journal:  J Am Coll Cardiol       Date:  2008-06-17       Impact factor: 24.094

8.  Living with long QT syndrome: a qualitative study of coping with increased risk of sudden cardiac death.

Authors:  Janice Andersen; Nina Øyen; Cathrine Bjorvatn; Eva Gjengedal
Journal:  J Genet Couns       Date:  2008-08-22       Impact factor: 2.537

9.  Identifying mental health services in clinical genetic settings.

Authors:  M Cappelli; M J Esplen; B J Wilson; M Dorval; J L Bottorff; M Ly; J C Carroll; J Allanson; E Humphreys; D Rayson
Journal:  Clin Genet       Date:  2009-10       Impact factor: 4.438

10.  Psychosocial impact of specialized cardiac genetic clinics for hypertrophic cardiomyopathy.

Authors:  Jodie Ingles; Joanne M Lind; Philayrath Phongsavan; Christopher Semsarian
Journal:  Genet Med       Date:  2008-02       Impact factor: 8.822

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  12 in total

Review 1.  New approaches to providing individualized diabetes care in the 21st century.

Authors:  Priscilla W Powell; Sarah D Corathers; Jennifer Raymond; Randi Streisand
Journal:  Curr Diabetes Rev       Date:  2015

2.  The accessibility and utilization of genetic testing for inherited heart rhythm disorders: a Canadian cross-sectional survey study.

Authors:  Thomas M Roston; Laura Dewar; Sonia Franciosi; Julie Hathaway; Kirsten Bartels; Taylor Cunningham; Karen A Gibbs; Sam Sheps; Zachary W M Laksman; Shubhayan Sanatani; Andrew D Krahn
Journal:  J Community Genet       Date:  2017-11-23

3.  Clinical Cardiovascular Genetic Counselors Take a Leading Role in Team-based Variant Classification.

Authors:  Chloe Reuter; Megan E Grove; Kate Orland; Katherine Spoonamore; Colleen Caleshu
Journal:  J Genet Couns       Date:  2017-12-12       Impact factor: 2.537

4.  Translating advances in cardiogenetics into effective clinical practice.

Authors:  Louise Bordeaux Silverstein; Marina Stolerman; Nadia Hidayatallah; Thomas McDonald; Christine A Walsh; Esma Paljevic; Lilian L Cohen; Robert W Marion; David Wasserman; Siobhan M Dolan
Journal:  Qual Health Res       Date:  2014-08-11

5.  Psychological stress associated with cardiogenetic conditions.

Authors:  Nadia Hidayatallah; Louise B Silverstein; Marina Stolerman; Thomas McDonald; Christine A Walsh; Esma Paljevic; Lilian L Cohen; Robert W Marion; David Wasserman; Sarah Hreyo; Siobhan M Dolan
Journal:  Per Med       Date:  2014-09-01       Impact factor: 2.512

6.  How do Physicians Decide to Refer Their Patients for Psychiatric Genetic Counseling? A Qualitative Study of Physicians' Practice.

Authors:  Emma Leach; Emily Morris; Hannah J White; Angela Inglis; Anna Lehman; Jehannine Austin
Journal:  J Genet Couns       Date:  2016-05-17       Impact factor: 2.537

7.  Motivation to pursue genetic testing in individuals with a personal or family history of cardiac events or sudden cardiac death.

Authors:  Kathleen E Erskine; Nadia Z Hidayatallah; Christine A Walsh; Thomas V McDonald; Lilian Cohen; Robert W Marion; Siobhan M Dolan
Journal:  J Genet Couns       Date:  2014-03-25       Impact factor: 2.537

Review 8.  The Role of an Integrated Multidisciplinary Clinic in the Management of Patients with Cutaneous Lymphoma.

Authors:  Kelly H Tyler; Bradley M Haverkos; Justin Hastings; Eileen Hu; Ramez Philips; Alejandro A Gru; Meng Xu Welliver; Anjali Mishra; Henry K Wong; Pierluigi Porcu
Journal:  Front Oncol       Date:  2015-06-17       Impact factor: 6.244

Review 9.  Channelopathies - emerging trends in the management of inherited arrhythmias.

Authors:  Priya Chockalingam; Yuka Mizusawa; Arthur Am Wilde
Journal:  Indian Pacing Electrophysiol J       Date:  2015-04-01

10.  Automatic referrals within a cystic fibrosis multidisciplinary clinic improve patient evaluation and management.

Authors:  Amy Darukhanavala; Ted Kremer
Journal:  J Clin Transl Endocrinol       Date:  2021-06-12
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