Literature DB >> 24491449

The role of key genes and pathways involved in the tumorigenesis of Malignant Mesothelioma.

Leonardo Vinícius Monteiro de Assis1, Jamille Locatelli2, Mauro César Isoldi3.   

Abstract

Malignant Mesothelioma (MM) is a very aggressive cancer with low survival rates and often diagnosed at an advanced stage. Several players have been implicated in the development of this cancer, such as asbestos, erionite and the simian virus 40 (SV40). Here, we have reviewed the involvement of erionite, SV40, as well as, the role of several genes (p16(INK4a), p14(ARF), NF2, LATS2, SAV, CTNNB1 and among others), the pathways (RAS, PI3K, Wnt, BCL and Hippo), and their respective roles in the development of MM.
Copyright © 2014 Elsevier B.V. All rights reserved.

Entities:  

Keywords:  Erionite/SV40; Genes and pathways; Malignant Mesothelioma; NF2; PI3K/AKT; p16(INK4a)/p(14ARF)

Mesh：

Substances：

Year:  2014        PMID： 24491449     DOI： 10.1016/j.bbcan.2014.01.008

Source DB:  PubMed          Journal:  Biochim Biophys Acta        ISSN： 0006-3002


  21 in total

1.  Current issues in malignant pleural mesothelioma evaluation and management.

Authors:  Jing Ai; James P Stevenson
Journal:  Oncologist       Date:  2014-07-24

2.  Establishment and mutation analysis of a novel malignant peritoneal mesothelioma cell line, TU-MM-1, using whole genome sequencing.

Authors:  Nao Oumi; Hiroaki Itamochi; Hiroaki Komatsu; Tetsuro Oishi; Muneaki Shimada; Shinya Sato; Jun Chikumi; Seiya Sato; Michiko Nonaka; Akiko Kudoh; Tasuku Harada
Journal:  Hum Cell       Date:  2015-06-13       Impact factor: 4.174

3.  The development of MM is strongly correlated with exposure to asbestos and erionite, as well as to simian virus 40”.

Authors:  Leonardo de Assis; Mauro César Isoldi
Journal:  J Bras Pneumol       Date:  2014-10       Impact factor: 2.624

4.  MiR-score: a novel 6-microRNA signature that predicts survival outcomes in patients with malignant pleural mesothelioma.

Authors:  Michaela B Kirschner; Yuen Yee Cheng; Nicola J Armstrong; Ruby C Y Lin; Steven C Kao; Anthony Linton; Sonja Klebe; Brian C McCaughan; Nico van Zandwijk; Glen Reid
Journal:  Mol Oncol       Date:  2014-12-02       Impact factor: 6.603

5.  Gender-Specific Molecular and Clinical Features Underlie Malignant Pleural Mesothelioma.

Authors:  Assunta De Rienzo; Michael A Archer; Beow Y Yeap; Nhien Dao; Daniele Sciaranghella; Antonios C Sideris; Yifan Zheng; Alexander G Holman; Yaoyu E Wang; Paola S Dal Cin; Jonathan A Fletcher; Renee Rubio; Larry Croft; John Quackenbush; Peter E Sugarbaker; Kiara J Munir; Jesse R Battilana; Corinne E Gustafson; Lucian R Chirieac; Soo Meng Ching; James Wong; Liang Chung Tay; Stephen Rudd; Robert Hercus; David J Sugarbaker; William G Richards; Raphael Bueno
Journal:  Cancer Res       Date:  2015-11-10       Impact factor: 12.701

6.  Association between P16INK4a promoter methylation and HNSCC: a meta-analysis of 21 published studies.

Authors:  Hao Shi; Xiong Chen; Cheng Lu; Changmei Gu; Hongwei Jiang; RuiWei Meng; Xun Niu; Yangxin Huang; Meixia Lu
Journal:  PLoS One       Date:  2015-04-02       Impact factor: 3.240

7.  Consistent gene expression profiles in MexTAg transgenic mouse and wild type mouse asbestos-induced mesothelioma.

Authors:  Cleo Robinson; Ian M Dick; Michael J Wise; Andrew Holloway; Dileepa Diyagama; Bruce W S Robinson; Jenette Creaney; Richard A Lake
Journal:  BMC Cancer       Date:  2015-12-18       Impact factor: 4.430

8.  Downregulation of TBXAS1 in an iron-induced malignant mesothelioma model.

Authors:  Daisuke Minami; Nagio Takigawa; Yuka Kato; Kenichiro Kudo; Hideko Isozaki; Shinsuke Hashida; Daijiro Harada; Nobuaki Ochi; Masanori Fujii; Toshio Kubo; Kadoaki Ohashi; Akiko Sato; Takehiro Tanaka; Katsuyuki Hotta; Masahiro Tabata; Shinichi Toyooka; Mitsune Tanimoto; Katsuyuki Kiura
Journal:  Cancer Sci       Date:  2015-09-19       Impact factor: 6.716

Review 9.  Overview of the biochemical and genetic processes in malignant mesothelioma.

Authors:  Leonardo Vinícius Monteiro de Assis; Mauro César Isoldi
Journal:  J Bras Pneumol       Date:  2014 Jul-Aug       Impact factor: 2.624

10.  A Tumor-Specific Neo-Antigen Caused by a Frameshift Mutation in BAP1 Is a Potential Personalized Biomarker in Malignant Peritoneal Mesothelioma.

Authors:  Jun Lai; Zhan Zhou; Xiao-Jing Tang; Zhi-Bin Gao; Jie Zhou; Shu-Qing Chen
Journal:  Int J Mol Sci       Date:  2016-05-14       Impact factor: 5.923
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