Literature DB >> 24490026

SMARTS (Systematic Monitoring of Adverse events Related to TreatmentS): The development of a pragmatic patient-completed checklist to assess antipsychotic drug side effects.

Peter M Haddad1, W Wolfgang Fleischhacker2, Joseph Peuskens3, Roberto Cavallaro4, Michael Ej Lean5, Margarita Morozova6, Gavin Reynolds7, Jean-Michel Azorin8, Pierre Thomas9, Hans-Jürgen Möller10.   

Abstract

OBJECTIVES: Antipsychotic drug side effects are common and can cause stigmatisation, decreased quality of life, poor adherence, and secondary morbidity and mortality. Systematic assessment of anticipated side effects is recommended as part of good clinical care, but is uncommon in practice and patients may not spontaneously report side effects. We aimed to develop a simple patient-completed checklist to screen systematically for potential antipsychotic side effects.
METHODS: The SMARTS checklist was developed over a series of group meetings by an international faculty of 12 experts (including psychiatrists, a general physician and a psychopharmacologist) based on their clinical experience and knowledge of the literature. The emphasis is on tolerability (i.e. assessment of side effects that 'trouble' the patient) as subjective impact of side effects is most relevant to medication adherence. The development took account of feedback from practising psychiatrists in Europe, the Middle East and Africa, a process that contributed to face validity.
RESULTS: The SMARTS checklist assesses whether patients are currently 'troubled' by 11 well-established potential antipsychotic side effects. Patients provide their responses to these questions by circling relevant side effects. An additional open question enquires about any other possible side effects. The checklist has been translated into Italian and Turkish.
CONCLUSIONS: The SMARTS checklist aims to strike a balance between brevity and capturing the most common and important antipsychotic side effects. It is appropriate for completion by patients prior to a clinical consultation, for example, in the waiting room. It can then form the focus for a more detailed clinical discussion about side effects. It can be used alone or form part of a more comprehensive assessment of antipsychotic side effects including blood tests and a physical examination when appropriate. The checklist assesses current problems and can be used longitudinally to assess change.

Entities:  

Keywords:  antipsychotics; checklist; rating scale; side effects; tolerability

Year:  2014        PMID: 24490026      PMCID: PMC3896136          DOI: 10.1177/2045125313510195

Source DB:  PubMed          Journal:  Ther Adv Psychopharmacol        ISSN: 2045-1253


  19 in total

1.  Prevalence and extent of distress of adverse effects of antipsychotics among callers to a United Kingdom National Mental Health Helpline.

Authors:  W K Fakhoury; D Wright; M Wallace
Journal:  Int Clin Psychopharmacol       Date:  2001-05       Impact factor: 1.659

2.  Tolerability of antipsychotics: recent controversies and future management.

Authors:  W Wolfgang Fleischhacker
Journal:  J Clin Psychiatry       Date:  2009-03-09       Impact factor: 4.384

3.  A rating scale for drug-induced akathisia.

Authors:  T R Barnes
Journal:  Br J Psychiatry       Date:  1989-05       Impact factor: 9.319

4.  Medication adherence and subjective weight perception in patients with first-episode psychotic disorder.

Authors:  Mimi M C Wong; E Y H Chen; Simon S Y Lui; Steve Tso
Journal:  Clin Schizophr Relat Psychoses       Date:  2011-10

5.  SAFTEE: a technique for the systematic assessment of side effects in clinical trials.

Authors:  J Levine; N R Schooler
Journal:  Psychopharmacol Bull       Date:  1986

6.  Impact of present and past antipsychotic side effects on attitude toward typical antipsychotic treatment and adherence.

Authors:  M Lambert; P Conus; P Eide; R Mass; A Karow; S Moritz; D Golks; D Naber
Journal:  Eur Psychiatry       Date:  2004-11       Impact factor: 5.361

7.  Patient-rated versus clinician-rated side effects of drug treatment in schizophrenia. Clinical validation of a self-rating version of the UKU Side Effect Rating Scale (UKU-SERS-Pat).

Authors:  E Lindström; T Lewander; U Malm; U F Malt; H Lublin; U G Ahlfors
Journal:  Nord J Psychiatry       Date:  2001       Impact factor: 2.202

Review 8.  Adverse effects of atypical antipsychotics : differential risk and clinical implications.

Authors:  Peter M Haddad; Sonu G Sharma
Journal:  CNS Drugs       Date:  2007       Impact factor: 5.749

9.  Cardiovascular disease and diabetes in people with severe mental illness position statement from the European Psychiatric Association (EPA), supported by the European Association for the Study of Diabetes (EASD) and the European Society of Cardiology (ESC).

Authors:  M De Hert; J M Dekker; D Wood; K G Kahl; R I G Holt; H-J Möller
Journal:  Eur Psychiatry       Date:  2009-08-13       Impact factor: 5.361

Review 10.  Neuroleptic dysphoria: towards a new synthesis.

Authors:  L Voruganti; A G Awad
Journal:  Psychopharmacology (Berl)       Date:  2003-11-27       Impact factor: 4.530

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Authors:  Maria Ferrara; Anya Umlauf; Chelsea Sanders; Jonathan M Meyer; John Allen McCutchan; Nichole Duarte; Joseph Hampton Atkinson; Igor Grant; Ronald J Ellis
Journal:  Psychiatry Res       Date:  2014-04-18       Impact factor: 3.222

2.  Check the effects: systematic assessment of antipsychotic side-effects in an inpatient cohort.

Authors:  Caroline Hynes; Stephen McWilliams; Mark Clarke; Ita Fitzgerald; Larkin Feeney; Mark Taylor; Fiona Boland; Dolores Keating
Journal:  Ther Adv Psychopharmacol       Date:  2020-09-25

3.  Measuring adherence to medication in schizophrenia: the relationship between attitudes toward drug therapy and plasma levels of new-generation antipsychotics.

Authors:  Nursen Yalcin-Siedentopf; Fabienne Wartelsteiner; Alexandra Kaufmann; Falko Biedermann; Monika Edlinger; Georg Kemmler; Maria A Rettenbacher; Christian G Widschwendter; Gerald Zernig; W Wolfgang Fleischhacker; Alex Hofer
Journal:  Int J Neuropsychopharmacol       Date:  2014-12-07       Impact factor: 5.176

Review 4.  Nonadherence with antipsychotic medication in schizophrenia: challenges and management strategies.

Authors:  Peter M Haddad; Cecilia Brain; Jan Scott
Journal:  Patient Relat Outcome Meas       Date:  2014-06-23

5.  Drug-induced Extrapyramidal Symptoms Scale (DIEPSS) Serbian Language version: Inter-rater and Test-retest Reliability.

Authors:  Ami Peljto; Ljubica Zamurovic; Milica Pejovic Milovancevic; Branko Aleksic; Dusica Lecic Tosevski; Toshiya Inada
Journal:  Sci Rep       Date:  2017-08-14       Impact factor: 4.379

6.  What side effects are problematic for patients prescribed antipsychotic medication? The Maudsley Side Effects (MSE) measure for antipsychotic medication.

Authors:  T Wykes; J Evans; C Paton; T R E Barnes; D Taylor; R Bentall; B Dalton; T Ruffell; D Rose; S Vitoratou
Journal:  Psychol Med       Date:  2017-04-19       Impact factor: 7.723

Review 7.  A Review of Methods for Monitoring Adverse Events in Pediatric Psychopharmacology Clinical Trials.

Authors:  Margaret Coates; Marina Spanos; Pooja Parmar; Tara Chandrasekhar; Linmarie Sikich
Journal:  Drug Saf       Date:  2018-05       Impact factor: 5.606

Review 8.  Patient-Reported Questionnaires to Identify Adverse Drug Reactions: A Systematic Review.

Authors:  Renly Lim; Lisa Kalisch Ellett; Elizabeth E Roughead; Phaik Yeong Cheah; Nashwa Masnoon
Journal:  Int J Environ Res Public Health       Date:  2021-11-12       Impact factor: 4.614

9.  Validation of the Glasgow Antipsychotic Side-Effect Scale (GASS) in an Italian Sample of Patients with Stable Schizophrenia and Bipolar Spectrum Disorders.

Authors:  Alessandro Rodolico; Carmen Concerto; Alessia Ciancio; Spyridon Siafis; Laura Fusar-Poli; Carla Benedicta Romano; Elisa Vita Scavo; Antonino Petralia; Salvatore Salomone; Maria Salvina Signorelli; Stefan Leucht; Eugenio Aguglia
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  9 in total

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