Shahla Yazdani1, Abolhasan Alijanpoor2, Majid Sharbatdaran3, Zinatossadat Bouzari1, Mohammad Abedisamakoosh4, Faranak Lakaieandi5, Mehdi Mohammadpour5. 1. Infertility and Reproductive Health Research Center, Babol University of Medical Sciences, Babol, Iran. 2. Department of Surgery, Babol University of Medical Sciences, Babol, Iran. 3. Department of Pathology, Babol University of Medical Sciences, Babol, Iran. 4. Department of Nephrology, Mazandaran University of Medical Sciences, Sari, Iran. 5. Babol University of Medical Sciences, Babol, Iran.
Abstract
BACKGROUND: CA125 levels in Meig's syndrome can increase or be normal which an unusual laboratory condition is. In this paper, we present a case of Meigs' syndrome associated with increased CA125 level due to ovarian fibroma / thecoma. CASE PRESENTATION: A 50-year old Iranian woman presented with fever, abdominal pain and distention and in imaging assessment, a 90×109 mm heterogeneous pelvic mass with free abdominopelvic fluid was reported. Pleural effusion was detected in CXR. Aspiration of ascetic fluid showed no evidence of malignancy. CA125 level was greater than 600 IU/mL. The patient went under laparotomy in which a 120×100 mm mass was detected in her left adnexa attached to colon, bowels and bottom of pelvis. Histology reported ovarian fibro/ thecoma. The mass was resected and after that, the symptoms disappeared and CA125 level reached to 15 IU/mL. The patient had no problem after 18 months of follow up. CONCLUSION: Meigs' syndrome should be considered at the differential diagnosis for a patient with pelvic mass, pleural effusion and ascites with normal cytology, increased CA125 levels.
BACKGROUND:CA125 levels in Meig's syndrome can increase or be normal which an unusual laboratory condition is. In this paper, we present a case of Meigs' syndrome associated with increased CA125 level due to ovarian fibroma / thecoma. CASE PRESENTATION: A 50-year old Iranian woman presented with fever, abdominal pain and distention and in imaging assessment, a 90×109 mm heterogeneous pelvic mass with free abdominopelvic fluid was reported. Pleural effusion was detected in CXR. Aspiration of ascetic fluid showed no evidence of malignancy. CA125 level was greater than 600 IU/mL. The patient went under laparotomy in which a 120×100 mm mass was detected in her left adnexa attached to colon, bowels and bottom of pelvis. Histology reported ovarian fibro/ thecoma. The mass was resected and after that, the symptoms disappeared and CA125 level reached to 15 IU/mL. The patient had no problem after 18 months of follow up. CONCLUSION: Meigs' syndrome should be considered at the differential diagnosis for a patient with pelvic mass, pleural effusion and ascites with normal cytology, increased CA125 levels.
Authors: Sabas Carlos Vieira; Leonardo Halley Carvalho Pimentel; José Carlos Castelo Branco Ribeiro; Argemiro Ferreira de Andrade Neto; Jerúsia Oliveira Ibiapina de Santana Journal: Sao Paulo Med J Date: 2003-11-05 Impact factor: 1.044
Authors: S Kudlacek; K Schieder; H Kölbl; W Neunteufel; C Nowotny; G Breitenecker; G Biegelmayer; M Vetterlein; B Fürlinger; M Micksche Journal: Gynecol Oncol Date: 1989-12 Impact factor: 5.482