Literature DB >> 24488415

Ultrasound of synovitis in rheumatoid arthritis: advantages of the dorsal over the palmar approach to finger joints.

Matthias N Witt1, Felix Mueller, Peter Weinert, Axel P Nigg, Christiane S Reindl, Fabian Proft, Hendrik Schulze-Koops, Mathias Grunke.   

Abstract

OBJECTIVE: To compare the dorsal and palmar ultrasound (US) examination of finger joints in early rheumatoid arthritis (RA) with regard to the concurrence of greyscale (GSUS) and power Doppler (PDUS) positivity, and to correlate both approaches with clinical variables.
METHODS: Patients with newly diagnosed RA were assessed by clinical examination and US. GSUS and PDUS of metacarpophalangeal (MCP) and proximal interphalangeal (PIP) joints were performed using the dorsal and palmar approach. Findings of synovitis in GSUS and PDUS were graded semiquantitatively from 0 to 3. Clinical and sonographic reevaluation was performed after 6 months.
RESULTS: With 44.6% versus 32.2% positive findings, palmar GSUS identified significantly more joints with synovitis than did dorsal GSUS. With 22.1% versus 8.9%, PDUS abnormalities were detected significantly more often from the dorsal side. With 71.2% versus 21.8% for the MCP and 57.5% versus 17.4% for the PIP joints, significantly more GSUS and PDUS double-positive joints were found with the dorsal as opposed to the palmar approach. These differences remained significant at Month 6. Both palmar and dorsal GSUS and PDUS correlated with comparable strength with clinical variables such as the Disease Activity Score 28, Clinical Disease Activity Index, and Simple Disease Activity Index.
CONCLUSION: Although the dorsal approach detected fewer GSUS findings than the palmar approach, PDUS signals were significantly more frequently detected by dorsal US. In addition, the prevalence of double-positive joints with concurrent GSUS and PDUS findings was significantly higher with the dorsal approach. These data argue in favor of the dorsal US approach to finger joints in RA.

Entities:  

Keywords:  EARLY RHEUMATOID ARTHRITIS; SYNOVITIS; ULTRASOUND

Mesh:

Year:  2014        PMID: 24488415     DOI: 10.3899/jrheum.131027

Source DB:  PubMed          Journal:  J Rheumatol        ISSN: 0315-162X            Impact factor:   4.666


  6 in total

1.  Evaluation of a Novel Semi-Automated Ultrasound System for the Detection of Synovitis: A Prospective Study involving 45 Patients with Rheumatoid Arthritis.

Authors:  M Witt; J Frielinghausen; R Mueller; F Mueller; F Proft; H Schulze-Koops; M Grunke; D-A Clevert
Journal:  Ultrasound Int Open       Date:  2016-09-14

Review 2.  [Biomarkers and imaging for diagnosis and stratification of rheumatoid arthritis and spondylarthritis in the BMBF consortium ArthroMark].

Authors:  T Häupl; A Skapenko; B Hoppe; K Skriner; H Burkhardt; D Poddubnyy; S Ohrndorf; P Sewerin; U Mansmann; B Stuhlmüller; H Schulze-Koops; G-R Burmester
Journal:  Z Rheumatol       Date:  2018-05       Impact factor: 1.372

Review 3.  The Role of Power Doppler Ultrasonography as Disease Activity Marker in Rheumatoid Arthritis.

Authors:  Shaloo Bhasin; Peter P Cheung
Journal:  Dis Markers       Date:  2015-05-03       Impact factor: 3.434

4.  Scoring ultrasound synovitis in rheumatoid arthritis: a EULAR-OMERACT ultrasound taskforce-Part 2: reliability and application to multiple joints of a standardised consensus-based scoring system.

Authors:  Lene Terslev; Esperanza Naredo; Philippe Aegerter; Richard J Wakefield; Marina Backhaus; Peter Balint; George A W Bruyn; Annamaria Iagnocco; Sandrine Jousse-Joulin; Wolfgang A Schmidt; Marcin Szkudlarek; Philip G Conaghan; Emilio Filippucci; Maria Antonietta D'Agostino
Journal:  RMD Open       Date:  2017-07-11

5.  Do musculoskeletal ultrasound and magnetic resonance imaging identify synovitis and tenosynovitis at the same joints and tendons? A comparative study in early inflammatory arthritis and clinically suspect arthralgia.

Authors:  Sarah Ohrndorf; Aleid C Boer; Debbie M Boeters; Robin M Ten Brinck; Gerd-R Burmester; Marion C Kortekaas; Annette H M van der Helm-van Mil
Journal:  Arthritis Res Ther       Date:  2019-02-14       Impact factor: 5.156

6.  Detecting inflammation in rheumatoid arthritis using Fourier transform analysis of dorsal optical transmission images from a pilot study.

Authors:  Daniel Lighter; Andrew Filer; Hamid Dehghani
Journal:  J Biomed Opt       Date:  2019-06       Impact factor: 3.170

  6 in total

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