OBJECTIVE: Evaluate the differences in achieving puberty between ADHD and non-ADHD participants and the effects of medication on that process among ADHD participants. PROCEDURE: A subset of participants with ADHD from the Multimodal Treatment study of ADHD (n = 342) were compared with respect to Tanner staging to participants from a comparison group without ADHD (n = 159) at the 36-month follow-up assessment. Further comparisons were made for Tanner stages and Auxology of the participants in the ADHD group who were always (n = 61), never (n = 56), newly (n = 74) and inconsistently (n = 116) treated with stimulants. RESULTS: No statistically significant differences in Tanner stages of sexual development were found between the ADHD and non-ADHD groups at the age of assessment (between 10 and 14 years of age) or among the ADHD medication subgroups, although a trend was observed for stimulant-associated delayed pubertal initiation using auxological analysis. CONCLUSION: Children with or without ADHD did not differ in Tanner stages at the 3-year follow-up assessment, and exposure to stimulant medication does not appear to affect sexual development within this age range.
OBJECTIVE: Evaluate the differences in achieving puberty between ADHD and non-ADHDparticipants and the effects of medication on that process among ADHDparticipants. PROCEDURE: A subset of participants with ADHD from the Multimodal Treatment study of ADHD (n = 342) were compared with respect to Tanner staging to participants from a comparison group without ADHD (n = 159) at the 36-month follow-up assessment. Further comparisons were made for Tanner stages and Auxology of the participants in the ADHD group who were always (n = 61), never (n = 56), newly (n = 74) and inconsistently (n = 116) treated with stimulants. RESULTS: No statistically significant differences in Tanner stages of sexual development were found between the ADHD and non-ADHD groups at the age of assessment (between 10 and 14 years of age) or among the ADHD medication subgroups, although a trend was observed for stimulant-associated delayed pubertal initiation using auxological analysis. CONCLUSION:Children with or without ADHD did not differ in Tanner stages at the 3-year follow-up assessment, and exposure to stimulant medication does not appear to affect sexual development within this age range.
Authors: Donald R Mattison; Tony M Plant; Hui-Min Lin; Hung-Chia Chen; James J Chen; Nathan C Twaddle; Daniel Doerge; William Slikker; Ralph E Patton; Charlotte E Hotchkiss; Ralph J Callicott; Steven M Schrader; Terry W Turner; James S Kesner; Benedetto Vitiello; Dayton M Petibone; Suzanne M Morris Journal: Proc Natl Acad Sci U S A Date: 2011-09-19 Impact factor: 11.205
Authors: Joseph Biederman; Stephen V Faraone; Michael C Monuteaux; Elizabeth A Plunkett; Julie Gifford; Thomas Spencer Journal: Pediatrics Date: 2003-05 Impact factor: 7.124
Authors: Priscilla Gregório Hertz; Daniel Turner; Steffen Barra; Laura Biedermann; Petra Retz-Junginger; Daniel Schöttle; Wolfgang Retz Journal: Front Psychiatry Date: 2022-05-16 Impact factor: 5.435