Literature DB >> 24486463

Electrochemical synthesis of glycoconjugates from activated sterol derivatives.

Aneta M Tomkiel1, Jan Kowalski2, Jolanta Płoszyńska2, Leszek Siergiejczyk1, Zenon Lotowski1, Andrzej Sobkowiak2, Jacek W Morzycki3.   

Abstract

Several derivatives of cholesterol and other 3β-hydroxy-Δ(5)-steroids were prepared and tested as sterol donors in electrochemical reactions with sugar alcohols. The reactions afforded glycoconjugates with sugar linked to a steroid moiety by an ether bond. Readily available sterol diphenylphosphates yielding up to 54% of the desired glycoconjugate were found to be the best sterol donors.
Copyright © 2014 Elsevier Inc. All rights reserved.

Entities:  

Keywords:  Activating groups; Cholesterol; Electrochemical oxidation; Glycosylation; Sterol glycoconjugates

Mesh：

Substances：

Year:  2014        PMID： 24486463     DOI： 10.1016/j.steroids.2014.01.007

Source DB:  PubMed          Journal:  Steroids        ISSN： 0039-128X            Impact factor:   2.668


  3 in total

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Authors:  Jacek W Morzycki; Andrzej Sobkowiak
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3.  3α,5α-Cyclocholestan-6β-yl ethers as donors of the cholesterol moiety for the electrochemical synthesis of cholesterol glycoconjugates.

Authors:  Aneta M Tomkiel; Adam Biedrzycki; Jolanta Płoszyńska; Dorota Naróg; Andrzej Sobkowiak; Jacek W Morzycki
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  3 in total

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