Literature DB >> 2448567

[Bone and soft tissue tumors--general strategy of therapy].

H P Bruch1.   

Abstract

Benign tumours, generally, don't cause problems to surgery. For palliative or curative therapy of malignant tumours, scrupulous planning is required whether to apply multimodal or monotherapy, an offensive or a defensive one. Latest study results proved optimal successes with multimodal therapy. Pre-operative radiotherapy, local or systemic chemotherapy, hyperthermic extremity perfusion and, recently, transcatheter embolization are in use. Mostly, sanitation succeeds by radical surgery with lymphadenectomy and distant metastases resection, if necessary, even without mutilations. Post-operative radiotherapy, chemotherapy and hyperthermic extremity perfusion turn against tumour residuals, cells neglected during surgery, micro- and macrometastases. Proximally, specific antibodies against surface antigens of tumour cells will be available. This strategy must even consider a retreat by symptomatic therapy with interferons, radiation, calcitonin, phenol injections and analgesics, in the advanced stages, completed by psychotherapeutic care which enables the patient to accept his disease.

Entities:  

Mesh:

Year:  1987        PMID: 2448567     DOI: 10.1007/bf01297831

Source DB:  PubMed          Journal:  Langenbecks Arch Chir        ISSN: 0023-8236


  16 in total

1.  Limb-sparing surgery for extremity sarcomas after preoperative intraarterial doxorubicin and radiation therapy.

Authors:  J E Goodnight; W L Bargar; T Voegeli; F W Blaisdell
Journal:  Am J Surg       Date:  1985-07       Impact factor: 2.565

2.  A retrospective study of the role of radiotherapy in the treatment of soft-tissue sarcoma.

Authors:  J A Dewar; W Duncan
Journal:  Clin Radiol       Date:  1985-11       Impact factor: 2.350

3.  Trends and variability in survival from osteosarcoma.

Authors:  W F Taylor; J C Ivins; D C Dahlin; J H Edmonson; D J Pritchard
Journal:  Mayo Clin Proc       Date:  1978-11       Impact factor: 7.616

Review 4.  Advances in the treatment of sarcomas of the extremity. Current status of limb salvage.

Authors:  F R Eilber; J Eckhardt; D L Morton
Journal:  Cancer       Date:  1984-12-01       Impact factor: 6.860

5.  Results of neutron therapy of soft-tissue sarcomas.

Authors:  H J Eichhorn; K H Dallüge
Journal:  Strahlentherapie       Date:  1985-12

6.  Improved survival for soft tissue sarcoma of the extremities by regional hyperthermic perfusion, local excision and radiation therapy.

Authors:  P M Lehti; H S Moseley; K Janoff; K Stevens; W S Fletcher
Journal:  Surg Gynecol Obstet       Date:  1986-02

7.  Preoperative, intraoperative, and postoperative radiation in the treatment of primary soft tissue sarcoma.

Authors:  H D Suit; H J Mankin; W C Wood; K H Proppe
Journal:  Cancer       Date:  1985-06-01       Impact factor: 6.860

8.  Soft tissue sarcomas of the distal extremities.

Authors:  M J Walker; D K Wood; H A Briele; J A Greager; M Patel; T K Das Gupta
Journal:  Surgery       Date:  1986-04       Impact factor: 3.982

9.  Radiation therapy for unresectable soft tissue sarcomas.

Authors:  J D Slater; M D McNeese; L J Peters
Journal:  Int J Radiat Oncol Biol Phys       Date:  1986-10       Impact factor: 7.038

10.  Radiation therapy of soft tissue sarcomas.

Authors:  J E Tepper; H D Suit
Journal:  Cancer       Date:  1985-05-01       Impact factor: 6.860

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