Literature DB >> 24485399

Gender-dependent associations of CDKN2A/2B, KCNJ11, POLI, SLC30A8, and TCF7L2 variants with type 2 diabetes in (North African) Tunisian Arabs.

Amira Turki1, Ghadeer S Al-Zaben2, Moncef Khirallah3, Hela Marmouch4, Touhami Mahjoub1, Wassim Y Almawi5.   

Abstract

We investigated the impact of gender on T2DM association with confirmed susceptibility loci. CDKN2A/2B rs10811661, KCNJ11 rs5219, and TCF7L2 rs7903146 were associated with T2DM in females, while POLI rs488846 was associated with T2DM among males; the association of SLC30A8 rs13266634 and TCF7L2 rs4506565, rs12243326, and rs12255372 with T2DM was gender-independent.
Copyright © 2014 Elsevier Ireland Ltd. All rights reserved.

Entities:  

Keywords:  Genetic association studies; Single nucleotide polymorphisms; Type 2 diabetes

Mesh：

Substances：

Year:  2014        PMID： 24485399     DOI： 10.1016/j.diabres.2013.12.040

Source DB:  PubMed          Journal:  Diabetes Res Clin Pract        ISSN： 0168-8227            Impact factor:   5.602


  10 in total

1.  CDC123/CAMK1D gene rs12779790 polymorphism and rs10811661 polymorphism upstream of the CDKN2A/2B gene in women with gestational diabetes.

Authors:  M Tarnowski; D Malinowski; K Safranow; V Dziedziejko; A Pawlik
Journal:  J Perinatol       Date:  2017-01-12       Impact factor: 2.521

2.  Gender differences in the association of ELMO1 genetic variants with type 2 diabetes in Tunisian Arabs.

Authors:  A Turki; S Mzoughi; N Mtitaoui; M Khairallah; H Marmouch; S Hammami; T Mahjoub; W Y Almawi
Journal:  J Endocrinol Invest       Date:  2017-07-27       Impact factor: 4.256

Review 3.  Islet biology, the CDKN2A/B locus and type 2 diabetes risk.

Authors:  Yahui Kong; Rohit B Sharma; Benjamin U Nwosu; Laura C Alonso
Journal:  Diabetologia       Date:  2016-05-07       Impact factor: 10.122

4.  Association of SLC30A8 gene polymorphism with type 2 diabetes, evidence from 46 studies: a meta-analysis.

Authors:  Mengdi Fan; Weimin Li; Lian Wang; Suping Gu; Sisi Dong; Mengdie Chen; Haimin Yin; Jinjue Zheng; Xiaoying Wu; Jian Jin; Xuchao Jiang; Jiao Cai; Peining Liu; Chao Zheng
Journal:  Endocrine       Date:  2016-02-01       Impact factor: 3.633

5.  Association of the Genetic Polymorphisms in Transcription Factor 7-Like 2 and Peroxisome Proliferator-Activated Receptors- γ 2 with Type 2 Diabetes Mellitus and is Interaction with Obesity Status in Emirati Population.

Authors:  Habiba Al-Safar; Ahmed Hassoun; Shaikha Almazrouei; Wala Kamal; Bachar Afandi; Naushad Rais
Journal:  J Diabetes Res       Date:  2015-07-27       Impact factor: 4.011

6.  Replication of KCNJ11 (p.E23K) and ABCC8 (p.S1369A) Association in Russian Diabetes Mellitus 2 Type Cohort and Meta-Analysis.

Authors:  Ekaterina Alekseevna Sokolova; Irina Arkadievna Bondar; Olesya Yurievna Shabelnikova; Olga Vladimirovna Pyankova; Maxim Leonidovich Filipenko
Journal:  PLoS One       Date:  2015-05-08       Impact factor: 3.240

7.  Opposite Genetic Effects of CMIP Polymorphisms on the Risk of Type 2 Diabetes and Obesity: A Family-Based Study in China.

Authors:  Yaying Cao; Tao Wang; Yiqun Wu; Juan Juan; Xueying Qin; Xun Tang; Tao Wu; Yonghua Hu
Journal:  Int J Mol Sci       Date:  2018-03-28       Impact factor: 5.923

8.  ZRANB3 is an African-specific type 2 diabetes locus associated with beta-cell mass and insulin response.

Authors:  Adebowale A Adeyemo; Norann A Zaghloul; Guanjie Chen; Ayo P Doumatey; Carmen C Leitch; Timothy L Hostelley; Jessica E Nesmith; Jie Zhou; Amy R Bentley; Daniel Shriner; Olufemi Fasanmade; Godfrey Okafor; Benjamin Eghan; Kofi Agyenim-Boateng; Settara Chandrasekharappa; Jokotade Adeleye; William Balogun; Samuel Owusu; Albert Amoah; Joseph Acheampong; Thomas Johnson; Johnnie Oli; Clement Adebamowo; Francis Collins; Georgia Dunston; Charles N Rotimi
Journal:  Nat Commun       Date:  2019-07-19       Impact factor: 14.919

9.  Association between SLC30A8 rs13266634 Polymorphism and Type 2 Diabetes Risk: A Meta-Analysis.

Authors:  Liqing Cheng; Dongmei Zhang; Lina Zhou; Jie Zhao; Bing Chen
Journal:  Med Sci Monit       Date:  2015-07-27

10.  Evaluation of Genome Wide Association Study Associated Type 2 Diabetes Susceptibility Loci in Sub Saharan Africans.

Authors:  Adebowale A Adeyemo; Fasil Tekola-Ayele; Ayo P Doumatey; Amy R Bentley; Guanjie Chen; Hanxia Huang; Jie Zhou; Daniel Shriner; Olufemi Fasanmade; Godfrey Okafor; Benjamin Eghan; Kofi Agyenim-Boateng; Jokotade Adeleye; Williams Balogun; Abdel Elkahloun; Settara Chandrasekharappa; Samuel Owusu; Albert Amoah; Joseph Acheampong; Thomas Johnson; Johnnie Oli; Clement Adebamowo; Francis Collins; Georgia Dunston; Charles N Rotimi
Journal:  Front Genet       Date:  2015-11-24       Impact factor: 4.599
  10 in total

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