| Literature DB >> 24485284 |
Kingston H G Mills1, Pádraig J Ross2, Aideen C Allen2, Mieszko M Wilk2.
Abstract
Bordetella pertussis causes whooping cough and is re-emerging in developed countries despite widespread immunization with acellular pertussis vaccines (Pa), which are less effective than the whole cell vaccines that they replaced. Efficacy of Pa could be improved by switching from alum to alternative adjuvants that generate more potent cell mediated immunity.Entities:
Keywords: Bordetella pertussis; Th1 cell; adjuvant; cell mediated immunity; vaccine; whooping cough
Mesh:
Substances:
Year: 2014 PMID: 24485284 DOI: 10.1016/j.tim.2013.11.007
Source DB: PubMed Journal: Trends Microbiol ISSN: 0966-842X Impact factor: 17.079